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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO10
All Species:
14.55
Human Site:
S375
Identified Species:
32
UniProt:
Q9UK96
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK96
NP_036298.2
956
105195
S375
D
Q
L
M
Y
R
L
S
Y
Q
V
Q
G
P
R
Chimpanzee
Pan troglodytes
XP_520584
1014
111075
S433
D
Q
L
M
Y
R
L
S
Y
Q
V
Q
G
P
R
Rhesus Macaque
Macaca mulatta
XP_001111119
1023
112176
S442
D
Q
L
M
Y
R
L
S
Y
Q
V
Q
G
P
R
Dog
Lupus familis
XP_538735
963
105501
S382
D
Q
L
T
Y
R
L
S
Y
Q
V
Q
G
P
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_001019313
950
104459
Q375
Y
R
L
S
Y
Q
V
Q
G
P
R
P
V
L
G
Rat
Rattus norvegicus
XP_001071167
950
104300
Q375
Y
R
L
S
Y
Q
V
Q
G
P
R
P
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510335
1118
121038
A424
N
E
D
D
D
Q
A
A
C
K
V
S
S
Y
Q
Chicken
Gallus gallus
XP_419357
1076
118785
G411
S
N
P
A
R
Y
K
G
R
E
N
M
L
Y
Y
Frog
Xenopus laevis
NP_001086604
843
94076
G311
A
V
C
V
S
G
Q
G
A
C
P
T
I
K
Q
Zebra Danio
Brachydanio rerio
NP_001128729
964
105168
G378
L
D
G
E
K
S
T
G
L
K
L
S
Y
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785605
875
96986
S340
V
G
A
A
V
S
V
S
G
R
R
A
S
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
92.6
95.1
N.A.
93.7
92.8
N.A.
54
20.7
20.6
52.7
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
94.1
93
97.3
N.A.
96.6
96.5
N.A.
66
35
35.8
70.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
6.6
0
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
46.6
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
0
0
10
10
10
0
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
37
10
10
10
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
10
0
28
28
0
0
0
37
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
19
0
0
0
10
0
% K
% Leu:
10
0
55
0
0
0
37
0
10
0
10
0
10
19
0
% L
% Met:
0
0
0
28
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
19
10
19
0
46
0
% P
% Gln:
0
37
0
0
0
28
10
19
0
37
0
37
0
0
28
% Q
% Arg:
0
19
0
0
10
37
0
0
10
10
28
0
0
0
37
% R
% Ser:
10
0
0
19
10
19
0
46
0
0
0
19
19
0
0
% S
% Thr:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
10
% T
% Val:
10
10
0
10
10
0
28
0
0
0
46
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
55
10
0
0
37
0
0
0
10
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _