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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO10 All Species: 22.73
Human Site: S726 Identified Species: 50
UniProt: Q9UK96 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK96 NP_036298.2 956 105195 S726 I T I A L V E S N S I N H N G
Chimpanzee Pan troglodytes XP_520584 1014 111075 S784 I T I A L V E S N S I N H N G
Rhesus Macaque Macaca mulatta XP_001111119 1023 112176 S793 I T I A L V E S N S I N H N G
Dog Lupus familis XP_538735 963 105501 S733 V T I A L V E S N S I N H N G
Cat Felis silvestris
Mouse Mus musculus NP_001019313 950 104459 S720 I T V A L V E S N S I N H N G
Rat Rattus norvegicus XP_001071167 950 104300 S720 V T V A L V E S N S I N H N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510335 1118 121038 I780 R S I S V A L I E S N S I N H
Chicken Gallus gallus XP_419357 1076 118785 Q789 N R I H S G K Q V G V Y F Y D
Frog Xenopus laevis NP_001086604 843 94076 G627 I F D N A M A G V W I K T D S
Zebra Danio Brachydanio rerio NP_001128729 964 105168 N734 I T V A L V E N N C I S Q N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785605 875 96986 M657 N E I F D N A M A G V W I K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 92.6 95.1 N.A. 93.7 92.8 N.A. 54 20.7 20.6 52.7 N.A. N.A. N.A. N.A. 21.1
Protein Similarity: 100 94.1 93 97.3 N.A. 96.6 96.5 N.A. 66 35 35.8 70.5 N.A. N.A. N.A. N.A. 37.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 20 6.6 13.3 66.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 46.6 20 26.6 86.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 64 10 10 19 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 0 0 0 64 0 10 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 19 0 0 0 0 64 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 55 0 10 % H
% Ile: 55 0 64 0 0 0 0 10 0 0 73 0 19 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 10 0 10 0 % K
% Leu: 0 0 0 0 64 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 10 0 10 0 10 64 0 10 55 0 73 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Q
% Arg: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 10 10 0 0 55 0 64 0 19 0 0 10 % S
% Thr: 0 64 0 0 0 0 0 0 0 0 0 0 10 0 10 % T
% Val: 19 0 28 0 10 64 0 0 19 0 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _