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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO10
All Species:
30.61
Human Site:
Y464
Identified Species:
67.33
UniProt:
Q9UK96
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK96
NP_036298.2
956
105195
Y464
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
N
Chimpanzee
Pan troglodytes
XP_520584
1014
111075
Y522
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
N
Rhesus Macaque
Macaca mulatta
XP_001111119
1023
112176
Y531
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
N
Dog
Lupus familis
XP_538735
963
105501
Y471
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_001019313
950
104459
Y460
N
V
F
R
N
L
T
Y
A
V
R
C
I
H
N
Rat
Rattus norvegicus
XP_001071167
950
104300
Y460
N
V
F
R
N
L
T
Y
A
V
R
C
I
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510335
1118
121038
Y518
S
I
F
R
D
L
T
Y
A
V
R
C
I
Q
N
Chicken
Gallus gallus
XP_419357
1076
118785
A537
S
T
C
T
V
G
S
A
V
C
V
S
G
Q
G
Frog
Xenopus laevis
NP_001086604
843
94076
H391
Y
F
E
S
C
N
I
H
R
N
R
I
A
G
F
Zebra Danio
Brachydanio rerio
NP_001128729
964
105168
Y461
N
V
F
R
G
L
N
Y
A
V
R
C
I
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785605
875
96986
C420
G
M
G
Y
F
D
R
C
D
I
H
H
N
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
92.6
95.1
N.A.
93.7
92.8
N.A.
54
20.7
20.6
52.7
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
94.1
93
97.3
N.A.
96.6
96.5
N.A.
66
35
35.8
70.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
0
6.6
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
13.3
80
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
73
0
0
0
10
0
0
% A
% Cys:
0
0
10
0
10
0
0
10
0
10
0
73
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
73
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
10
10
0
0
0
0
0
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
10
0
55
0
% H
% Ile:
0
46
0
0
0
0
10
0
0
10
0
10
73
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
0
0
0
55
10
10
0
0
10
0
0
10
0
73
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% Q
% Arg:
0
0
0
73
0
0
10
0
10
0
82
0
0
10
0
% R
% Ser:
19
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% S
% Thr:
0
10
0
10
0
0
64
0
0
0
0
0
0
0
0
% T
% Val:
0
28
0
0
10
0
0
0
10
73
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _