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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO3
All Species:
18.79
Human Site:
S445
Identified Species:
41.33
UniProt:
Q9UK99
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK99
NP_036307.2
471
54561
S445
D
S
A
D
M
D
E
S
D
E
D
D
E
E
E
Chimpanzee
Pan troglodytes
XP_001145061
415
47659
R398
I
F
N
V
A
I
P
R
F
H
M
A
C
P
T
Rhesus Macaque
Macaca mulatta
XP_001082360
471
54559
S445
D
S
A
D
M
D
E
S
D
E
D
D
E
E
E
Dog
Lupus familis
XP_849256
471
54485
S445
D
S
A
D
M
D
E
S
D
E
D
D
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC63
480
55209
S444
D
S
A
D
M
D
E
S
D
E
S
D
A
D
E
Rat
Rattus norvegicus
NP_001103076
480
55337
S444
D
S
A
D
M
D
E
S
D
E
S
D
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507536
410
47443
R393
I
F
N
V
T
I
P
R
F
H
M
V
C
P
T
Chicken
Gallus gallus
XP_427051
489
56204
R472
D
T
D
E
Y
E
D
R
R
R
V
M
D
I
P
Frog
Xenopus laevis
NP_001087177
449
51829
E430
S
T
D
T
D
D
Y
E
E
R
R
R
F
L
D
Zebra Danio
Brachydanio rerio
NP_001018538
356
40704
V339
A
N
G
N
V
E
E
V
R
G
P
G
V
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782760
301
34195
T284
L
S
R
H
W
E
I
T
D
S
S
G
Q
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
99.5
98.9
N.A.
92.5
93.1
N.A.
71.9
72.1
66.2
55.8
N.A.
N.A.
N.A.
N.A.
22
Protein Similarity:
100
87.9
99.7
99.7
N.A.
96
96.2
N.A.
79.8
81.5
77.4
68.1
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
0
100
100
N.A.
80
86.6
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
100
N.A.
86.6
93.3
N.A.
0
40
26.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
46
0
10
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% C
% Asp:
55
0
19
46
10
55
10
0
55
0
28
46
10
19
10
% D
% Glu:
0
0
0
10
0
28
55
10
10
46
0
0
37
28
46
% E
% Phe:
0
19
0
0
0
0
0
0
19
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
19
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
19
0
0
0
0
10
% H
% Ile:
19
0
0
0
0
19
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
46
0
0
0
0
0
19
10
0
0
0
% M
% Asn:
0
10
19
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
19
0
0
0
10
0
0
19
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
28
19
19
10
10
0
0
0
% R
% Ser:
10
55
0
0
0
0
0
46
0
10
28
0
0
0
0
% S
% Thr:
0
19
0
10
10
0
0
10
0
0
0
0
0
0
19
% T
% Val:
0
0
0
19
10
0
0
10
0
0
10
10
10
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _