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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO3 All Species: 29.09
Human Site: Y223 Identified Species: 64
UniProt: Q9UK99 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK99 NP_036307.2 471 54561 Y223 R N K N E V F Y Q C P D Q M A
Chimpanzee Pan troglodytes XP_001145061 415 47659 T197 L K Y C L P L T F C I H T G L
Rhesus Macaque Macaca mulatta XP_001082360 471 54559 Y223 R N K N E V F Y Q C P D Q M A
Dog Lupus familis XP_849256 471 54485 Y223 R N K N E V F Y Q C P D Q M A
Cat Felis silvestris
Mouse Mus musculus Q9DC63 480 55209 Y223 R N K N E V F Y Q C P D Q M A
Rat Rattus norvegicus NP_001103076 480 55337 Y223 R N K N E V F Y Q C P D Q M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507536 410 47443 T192 L K Q C L P L T F C I H T G L
Chicken Gallus gallus XP_427051 489 56204 Y258 R N K Y E I F Y Q C P D Q M A
Frog Xenopus laevis NP_001087177 449 51829 Y219 R R R N E I F Y Q C P D Q T A
Zebra Danio Brachydanio rerio NP_001018538 356 40704 Y138 G C K L P N D Y R C S Y R I H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782760 301 34195 G83 K K W G K Y M G C Y V K V K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 99.5 98.9 N.A. 92.5 93.1 N.A. 71.9 72.1 66.2 55.8 N.A. N.A. N.A. N.A. 22
Protein Similarity: 100 87.9 99.7 99.7 N.A. 96 96.2 N.A. 79.8 81.5 77.4 68.1 N.A. N.A. N.A. N.A. 36.3
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 86.6 73.3 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 13.3 93.3 86.6 40 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % A
% Cys: 0 10 0 19 0 0 0 0 10 91 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 64 0 0 0 % D
% Glu: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 64 0 19 0 0 0 0 0 0 % F
% Gly: 10 0 0 10 0 0 0 10 0 0 0 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 10 % H
% Ile: 0 0 0 0 0 19 0 0 0 0 19 0 0 10 0 % I
% Lys: 10 28 64 0 10 0 0 0 0 0 0 10 0 10 0 % K
% Leu: 19 0 0 10 19 0 19 0 0 0 0 0 0 0 19 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 55 0 % M
% Asn: 0 55 0 55 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 19 0 0 0 0 64 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 64 0 0 0 64 0 0 % Q
% Arg: 64 10 10 0 0 0 0 0 10 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 19 0 0 0 0 19 10 0 % T
% Val: 0 0 0 0 0 46 0 0 0 0 10 0 10 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 10 0 73 0 10 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _