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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO3 All Species: 26.06
Human Site: Y252 Identified Species: 57.33
UniProt: Q9UK99 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK99 NP_036307.2 471 54561 Y252 F T D W F T S Y V K N V V S G
Chimpanzee Pan troglodytes XP_001145061 415 47659 E220 A E G R N K N E V F Y Q C P D
Rhesus Macaque Macaca mulatta XP_001082360 471 54559 Y252 F T D W F T S Y V K N V V S G
Dog Lupus familis XP_849256 471 54485 Y252 F T D W F T S Y V N N V V S G
Cat Felis silvestris
Mouse Mus musculus Q9DC63 480 55209 Y252 F T D W F T S Y V N N V V S G
Rat Rattus norvegicus NP_001103076 480 55337 Y252 F T D W F T S Y V N N V V S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507536 410 47443 E215 V E G R N Q Y E I F Y Q C P D
Chicken Gallus gallus XP_427051 489 56204 Y287 Y L E W F T S Y V N K V V T G
Frog Xenopus laevis NP_001087177 449 51829 Y248 F S Q W F T S Y V Q H V V S G
Zebra Danio Brachydanio rerio NP_001018538 356 40704 L161 G L M G S M A L S N H Y R S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782760 301 34195 T106 L E E R S P G T R T S L R G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 99.5 98.9 N.A. 92.5 93.1 N.A. 71.9 72.1 66.2 55.8 N.A. N.A. N.A. N.A. 22
Protein Similarity: 100 87.9 99.7 99.7 N.A. 96 96.2 N.A. 79.8 81.5 77.4 68.1 N.A. N.A. N.A. N.A. 36.3
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. 0 60 73.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. 6.6 80 93.3 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % C
% Asp: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 19 % D
% Glu: 0 28 19 0 0 0 0 19 0 0 0 0 0 0 10 % E
% Phe: 55 0 0 0 64 0 0 0 0 19 0 0 0 0 0 % F
% Gly: 10 0 19 10 0 0 10 0 0 0 0 0 0 10 64 % G
% His: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 19 10 0 0 0 0 % K
% Leu: 10 19 0 0 0 0 0 10 0 0 0 10 0 0 0 % L
% Met: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 10 0 0 46 46 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 19 10 % P
% Gln: 0 0 10 0 0 10 0 0 0 10 0 19 0 0 0 % Q
% Arg: 0 0 0 28 0 0 0 0 10 0 0 0 19 0 0 % R
% Ser: 0 10 0 0 19 0 64 0 10 0 10 0 0 64 0 % S
% Thr: 0 46 0 0 0 64 0 10 0 10 0 0 0 10 0 % T
% Val: 10 0 0 0 0 0 0 0 73 0 0 64 64 0 0 % V
% Trp: 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 64 0 0 19 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _