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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO3 All Species: 24.85
Human Site: Y379 Identified Species: 54.67
UniProt: Q9UK99 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK99 NP_036307.2 471 54561 Y379 T S G Y M E G Y Y T F H F L Y
Chimpanzee Pan troglodytes XP_001145061 415 47659 V340 I T N A K G D V E E V Q G P G
Rhesus Macaque Macaca mulatta XP_001082360 471 54559 Y379 T S G Y M E G Y Y T F H F L Y
Dog Lupus familis XP_849256 471 54485 Y379 T S G Y M E G Y Y T F H F L Y
Cat Felis silvestris
Mouse Mus musculus Q9DC63 480 55209 Y379 T S G Y M E G Y Y T F H F L Y
Rat Rattus norvegicus NP_001103076 480 55337 Y379 T S G Y M E G Y Y T F H F L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507536 410 47443 V335 I T N A K G D V E E V Q G P G
Chicken Gallus gallus XP_427051 489 56204 Y414 T S G Y M E G Y Y T F H C L Y
Frog Xenopus laevis NP_001087177 449 51829 M372 F S T S S G Y M E G Y Y T F H
Zebra Danio Brachydanio rerio NP_001018538 356 40704 T281 V A T T G D I T V S V S T S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782760 301 34195 Y226 R R Q K F A G Y F V V A S S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 99.5 98.9 N.A. 92.5 93.1 N.A. 71.9 72.1 66.2 55.8 N.A. N.A. N.A. N.A. 22
Protein Similarity: 100 87.9 99.7 99.7 N.A. 96 96.2 N.A. 79.8 81.5 77.4 68.1 N.A. N.A. N.A. N.A. 36.3
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 93.3 6.6 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 93.3 26.6 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 19 0 10 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 10 19 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 55 0 0 28 19 0 0 0 0 0 % E
% Phe: 10 0 0 0 10 0 0 0 10 0 55 0 46 10 10 % F
% Gly: 0 0 55 0 10 28 64 0 0 10 0 0 19 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 10 % H
% Ile: 19 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 19 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % L
% Met: 0 0 0 0 55 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 19 0 0 0 % Q
% Arg: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 64 0 10 10 0 0 0 0 10 0 10 10 19 0 % S
% Thr: 55 19 19 10 0 0 0 10 0 55 0 0 19 0 0 % T
% Val: 10 0 0 0 0 0 0 19 10 10 37 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 55 0 0 10 64 55 0 10 10 0 0 64 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _