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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO3
All Species:
18.79
Human Site:
Y420
Identified Species:
41.33
UniProt:
Q9UK99
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK99
NP_036307.2
471
54561
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001145061
415
47659
E377
S
T
T
S
G
Y
M
E
G
Y
Y
T
F
H
F
Rhesus Macaque
Macaca mulatta
XP_001082360
471
54559
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
E
Dog
Lupus familis
XP_849256
471
54485
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC63
480
55209
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
A
Rat
Rattus norvegicus
NP_001103076
480
55337
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507536
410
47443
E372
S
T
T
S
G
Y
M
E
G
H
Y
T
F
H
F
Chicken
Gallus gallus
XP_427051
489
56204
N451
S
T
A
R
M
E
T
N
H
N
E
Y
A
V
D
Frog
Xenopus laevis
NP_001087177
449
51829
T409
F
R
V
S
N
I
S
T
E
E
S
C
N
D
C
Zebra Danio
Brachydanio rerio
NP_001018538
356
40704
K318
A
K
S
A
L
P
E
K
A
C
Q
L
D
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782760
301
34195
H263
I
T
R
I
C
K
I
H
S
R
V
L
T
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
99.5
98.9
N.A.
92.5
93.1
N.A.
71.9
72.1
66.2
55.8
N.A.
N.A.
N.A.
N.A.
22
Protein Similarity:
100
87.9
99.7
99.7
N.A.
96
96.2
N.A.
79.8
81.5
77.4
68.1
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
10
0
0
0
10
0
19
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
46
0
0
0
0
0
0
10
10
10
% D
% Glu:
0
46
0
0
0
10
55
19
55
55
10
46
46
46
28
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
19
0
19
% F
% Gly:
0
0
0
46
19
0
0
0
19
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
10
10
0
0
0
19
0
% H
% Ile:
10
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
46
0
0
0
10
0
0
0
0
0
0
19
0
10
0
% L
% Met:
0
0
46
0
10
0
19
0
0
0
46
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
10
0
0
10
0
10
% N
% Pro:
0
0
0
0
46
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
10
10
0
0
0
0
0
10
0
0
0
0
10
% R
% Ser:
28
0
10
28
0
0
10
0
10
0
10
0
0
10
0
% S
% Thr:
0
37
19
0
0
0
10
10
0
0
0
19
10
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
46
0
10
19
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _