KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL5
All Species:
22.42
Human Site:
S297
Identified Species:
54.81
UniProt:
Q9UKA1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA1
NP_036293.1
691
78555
S297
E
D
A
D
I
D
E
S
E
E
S
A
E
E
S
Chimpanzee
Pan troglodytes
XP_517113
957
106564
S563
E
D
A
D
I
D
E
S
E
E
S
A
E
E
S
Rhesus Macaque
Macaca mulatta
XP_001118937
742
83595
S348
E
D
A
D
I
D
E
S
E
E
S
P
E
E
S
Dog
Lupus familis
XP_536232
691
78353
S297
E
D
A
D
I
D
E
S
E
E
S
A
E
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2S5
690
77875
S297
E
D
A
D
I
D
E
S
E
E
S
A
E
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505873
596
67886
V211
E
L
G
R
C
S
Q
V
S
T
K
W
S
Q
L
Chicken
Gallus gallus
XP_420776
687
78026
S296
E
D
A
D
I
D
E
S
E
E
A
A
E
D
S
Frog
Xenopus laevis
Q6INS1
678
76855
D291
A
Y
Q
E
W
D
E
D
A
D
I
D
E
S
E
Zebra Danio
Brachydanio rerio
Q2YDQ5
679
75714
E293
R
A
Y
Q
E
W
D
E
D
A
D
V
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788308
646
72217
K261
A
R
D
P
S
V
W
K
H
L
Y
P
S
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72
91.7
96.2
N.A.
93.6
N.A.
N.A.
73.2
80.4
66.5
56.4
N.A.
N.A.
N.A.
N.A.
39
Protein Similarity:
100
72
92.5
98.2
N.A.
96.3
N.A.
N.A.
78.4
89.5
79.1
70
N.A.
N.A.
N.A.
N.A.
54.1
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
6.6
86.6
20
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
20
100
33.3
33.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
60
0
0
0
0
0
10
10
10
50
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
10
60
0
70
10
10
10
10
10
10
10
10
0
% D
% Glu:
70
0
0
10
10
0
70
10
60
60
0
0
70
60
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
60
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% P
% Gln:
0
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
10
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
10
0
60
10
0
50
0
20
10
70
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
10
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _