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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL4
All Species:
22.42
Human Site:
T335
Identified Species:
44.85
UniProt:
Q9UKA2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA2
NP_036292.2
621
70097
T335
Y
W
A
K
L
D
D
T
S
L
E
F
L
Q
S
Chimpanzee
Pan troglodytes
XP_001136579
621
70122
T335
Y
W
A
K
L
G
D
T
S
L
E
F
L
Q
S
Rhesus Macaque
Macaca mulatta
XP_001082137
621
70349
T335
Y
W
A
K
L
D
D
T
S
L
E
F
L
Q
S
Dog
Lupus familis
XP_539053
621
70269
T335
Y
W
A
K
L
N
D
T
S
L
E
F
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH70
621
70250
T335
Y
W
A
R
L
D
D
T
S
L
E
F
L
Q
A
Rat
Rattus norvegicus
NP_001101389
290
32919
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507895
615
69422
E332
K
L
N
D
A
S
L
E
Y
L
Q
T
R
C
S
Chicken
Gallus gallus
XP_419825
620
70379
T334
Y
W
A
R
I
N
D
T
S
L
E
H
L
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007316
607
68628
C324
R
L
T
D
A
S
L
C
H
L
Q
S
R
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572951
669
75721
E381
Y
W
D
V
A
S
S
E
L
L
C
T
L
A
R
Honey Bee
Apis mellifera
XP_624129
540
61970
N257
I
P
N
T
T
E
Q
N
N
S
L
Q
K
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188402
503
56392
S220
L
V
F
D
H
R
Y
S
D
Y
Y
T
E
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.7
95.3
N.A.
93.4
42.5
N.A.
80.5
86.4
N.A.
66.9
N.A.
28.8
30.7
N.A.
30.7
Protein Similarity:
100
99.3
99
97.5
N.A.
97
45
N.A.
89
93.2
N.A.
80.1
N.A.
45.8
46.5
N.A.
47.9
P-Site Identity:
100
93.3
100
86.6
N.A.
86.6
0
N.A.
13.3
73.3
N.A.
6.6
N.A.
26.6
0
N.A.
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
0
N.A.
20
93.3
N.A.
20
N.A.
26.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
25
0
0
0
0
0
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
9
0
0
17
0
% C
% Asp:
0
0
9
25
0
25
50
0
9
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
9
0
17
0
0
50
0
9
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
42
0
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
34
0
0
0
0
0
0
0
0
9
9
0
% K
% Leu:
9
17
0
0
42
0
17
0
9
75
9
0
59
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
17
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
17
9
0
50
0
% Q
% Arg:
9
0
0
17
0
9
0
0
0
0
0
0
17
0
9
% R
% Ser:
0
0
0
0
0
25
9
9
50
9
0
9
0
0
42
% S
% Thr:
0
0
9
9
9
0
0
50
0
0
0
25
0
0
9
% T
% Val:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
59
0
0
0
0
0
9
0
9
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _