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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL4
All Species:
26.67
Human Site:
T493
Identified Species:
53.33
UniProt:
Q9UKA2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA2
NP_036292.2
621
70097
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Chimpanzee
Pan troglodytes
XP_001136579
621
70122
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001082137
621
70349
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Dog
Lupus familis
XP_539053
621
70269
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH70
621
70250
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Rat
Rattus norvegicus
NP_001101389
290
32919
S163
A
C
S
A
N
P
Y
S
P
N
P
P
A
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507895
615
69422
E488
W
R
C
K
N
V
T
E
S
G
M
A
Q
L
A
Chicken
Gallus gallus
XP_419825
620
70379
T492
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007316
607
68628
E480
W
R
C
R
N
L
S
E
R
G
L
A
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572951
669
75721
S540
L
W
K
A
H
F
L
S
S
R
G
L
Q
S
L
Honey Bee
Apis mellifera
XP_624129
540
61970
R413
T
L
T
P
Q
G
V
R
A
L
A
H
C
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188402
503
56392
V376
R
A
K
T
L
S
F
V
G
L
G
Y
L
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.7
95.3
N.A.
93.4
42.5
N.A.
80.5
86.4
N.A.
66.9
N.A.
28.8
30.7
N.A.
30.7
Protein Similarity:
100
99.3
99
97.5
N.A.
97
45
N.A.
89
93.2
N.A.
80.1
N.A.
45.8
46.5
N.A.
47.9
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
0
100
N.A.
0
N.A.
26.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
0
100
N.A.
6.6
N.A.
53.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
0
0
0
0
9
0
9
17
59
9
17
% A
% Cys:
0
9
17
50
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
17
50
0
0
0
9
59
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
17
67
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
17
9
50
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
59
9
0
0
9
9
9
0
0
17
9
9
9
17
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
25
50
0
0
0
59
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
9
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
9
17
50
9
0
0
0
9
9
9
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
9
9
17
17
0
0
0
0
9
0
% S
% Thr:
9
0
9
9
0
0
9
50
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
9
9
9
0
0
0
0
0
0
17
% V
% Trp:
17
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _