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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL4
All Species:
22.73
Human Site:
T569
Identified Species:
45.45
UniProt:
Q9UKA2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA2
NP_036292.2
621
70097
T569
Q
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Chimpanzee
Pan troglodytes
XP_001136579
621
70122
T569
Q
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001082137
621
70349
T569
Q
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Dog
Lupus familis
XP_539053
621
70269
T569
R
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH70
621
70250
T569
Q
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Rat
Rattus norvegicus
NP_001101389
290
32919
A239
P
L
L
S
L
K
T
A
L
V
D
M
N
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507895
615
69422
R564
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
L
Chicken
Gallus gallus
XP_419825
620
70379
T568
R
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007316
607
68628
R556
H
L
D
I
L
G
T
R
M
V
S
S
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572951
669
75721
L616
Q
L
D
L
M
G
I
L
N
I
T
H
E
R
V
Honey Bee
Apis mellifera
XP_624129
540
61970
I489
A
R
S
L
T
P
D
I
C
Y
G
I
L
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188402
503
56392
R452
L
D
L
L
G
A
Q
R
V
S
L
N
G
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.7
95.3
N.A.
93.4
42.5
N.A.
80.5
86.4
N.A.
66.9
N.A.
28.8
30.7
N.A.
30.7
Protein Similarity:
100
99.3
99
97.5
N.A.
97
45
N.A.
89
93.2
N.A.
80.1
N.A.
45.8
46.5
N.A.
47.9
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
6.6
93.3
N.A.
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
26.6
100
N.A.
26.6
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
9
0
0
0
0
17
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
25
50
0
0
9
0
0
0
9
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
9
25
50
0
0
0
9
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
17
50
0
9
9
0
9
0
9
0
9
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
34
67
25
25
50
0
9
9
0
9
0
9
9
25
% L
% Met:
0
0
0
0
9
0
0
0
17
50
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
9
9
0
0
% N
% Pro:
9
0
0
0
0
9
0
0
0
0
0
9
50
0
0
% P
% Gln:
50
50
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
17
9
0
0
0
0
0
25
50
0
0
0
0
9
0
% R
% Ser:
0
0
9
9
0
0
0
0
0
9
17
59
0
17
50
% S
% Thr:
0
0
0
0
9
0
25
50
0
0
9
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
9
25
50
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _