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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL4
All Species:
21.52
Human Site:
Y279
Identified Species:
43.03
UniProt:
Q9UKA2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA2
NP_036292.2
621
70097
Y279
G
E
G
P
N
N
G
Y
F
D
K
L
P
Y
E
Chimpanzee
Pan troglodytes
XP_001136579
621
70122
Y279
G
E
G
P
N
N
G
Y
F
D
K
L
P
Y
E
Rhesus Macaque
Macaca mulatta
XP_001082137
621
70349
Y279
R
E
G
P
N
N
G
Y
F
D
K
L
P
Y
E
Dog
Lupus familis
XP_539053
621
70269
Y279
R
E
G
P
N
N
G
Y
F
D
K
L
P
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH70
621
70250
Y279
G
D
G
P
H
N
G
Y
F
D
K
L
P
Y
E
Rat
Rattus norvegicus
NP_001101389
290
32919
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507895
615
69422
K276
T
N
I
G
Y
F
D
K
L
P
Y
E
L
I
Q
Chicken
Gallus gallus
XP_419825
620
70379
Y278
R
E
W
P
S
N
G
Y
F
D
K
L
P
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007316
607
68628
R268
L
A
N
G
Y
F
D
R
L
P
Y
E
L
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572951
669
75721
C325
E
A
A
A
P
Q
I
C
L
T
D
L
P
F
E
Honey Bee
Apis mellifera
XP_624129
540
61970
V201
L
S
Q
E
L
G
K
V
I
D
N
V
S
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188402
503
56392
H164
A
G
E
A
D
D
K
H
F
Q
P
Q
M
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.7
95.3
N.A.
93.4
42.5
N.A.
80.5
86.4
N.A.
66.9
N.A.
28.8
30.7
N.A.
30.7
Protein Similarity:
100
99.3
99
97.5
N.A.
97
45
N.A.
89
93.2
N.A.
80.1
N.A.
45.8
46.5
N.A.
47.9
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
0
80
N.A.
0
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
0
N.A.
6.6
86.6
N.A.
6.6
N.A.
26.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
17
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
9
17
0
0
59
9
0
0
0
0
% D
% Glu:
9
42
9
9
0
0
0
0
0
0
0
17
0
0
59
% E
% Phe:
0
0
0
0
0
17
0
0
59
0
0
0
0
17
0
% F
% Gly:
25
9
42
17
0
9
50
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
9
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
0
0
17
9
0
0
50
0
0
9
0
% K
% Leu:
17
0
0
0
9
0
0
0
25
0
0
59
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
9
0
34
50
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
50
9
0
0
0
0
17
9
0
59
0
0
% P
% Gln:
0
0
9
0
0
9
0
0
0
9
0
9
0
0
17
% Q
% Arg:
25
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
9
0
0
0
0
0
0
0
9
0
9
% S
% Thr:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
50
0
0
17
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _