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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP11
All Species:
18.48
Human Site:
S422
Identified Species:
50.83
UniProt:
Q9UKA4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKA4
NP_057332.1
1901
210512
S422
P
T
P
R
K
P
E
S
P
Y
G
N
L
C
D
Chimpanzee
Pan troglodytes
XP_001151723
1901
210231
S422
P
T
P
R
K
P
E
S
P
Y
G
N
L
C
D
Rhesus Macaque
Macaca mulatta
XP_001091086
1925
211593
S422
P
T
P
R
K
P
E
S
P
Y
G
N
L
C
D
Dog
Lupus familis
XP_851781
1940
214708
S473
P
T
P
R
K
P
E
S
P
Y
S
N
L
C
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_001157975
1894
208743
P418
A
N
V
R
K
P
T
P
R
K
P
E
S
P
Y
Rat
Rattus norvegicus
Q62924
1129
124463
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507739
1999
220560
S478
P
T
P
R
K
P
E
S
P
F
S
S
L
Y
D
Chicken
Gallus gallus
XP_417031
1956
217183
S443
S
V
F
E
V
P
D
S
P
R
P
V
K
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686916
1795
196467
K385
T
T
G
M
N
P
H
K
F
D
H
R
T
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
91.7
79.9
N.A.
74.1
39.5
N.A.
53.8
52.6
N.A.
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
94.6
87
N.A.
83.1
48
N.A.
67.3
68.8
N.A.
57.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
20
0
N.A.
73.3
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
0
N.A.
86.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
56
% D
% Glu:
0
0
0
12
0
0
56
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
67
0
0
12
0
12
0
0
12
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
56
12
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
12
0
0
0
0
0
0
45
0
0
0
% N
% Pro:
56
0
56
0
0
89
0
12
67
0
23
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
67
0
0
0
0
12
12
0
12
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
67
0
0
23
12
12
0
12
% S
% Thr:
12
67
0
0
0
0
12
0
0
0
0
0
12
12
0
% T
% Val:
0
12
12
0
12
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
45
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _