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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXW11 All Species: 19.09
Human Site: S237 Identified Species: 35
UniProt: Q9UKB1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKB1 NP_036432.2 542 62091 S237 L Q R I Q C R S E N S K G V Y
Chimpanzee Pan troglodytes XP_518097 563 64534 S258 L Q R I Q C R S E N S K G V Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852961 563 64548 S258 L Q R I Q C R S E N S K G V Y
Cat Felis silvestris
Mouse Mus musculus Q3ULA2 605 68904 S300 L Q R I H C R S E T S K G V Y
Rat Rattus norvegicus Q5BK30 415 45841 A141 R N V V Y A I A F N N P Y G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508141 638 72675 S333 L Q R I Q C R S E N S K G V Y
Chicken Gallus gallus Q9PTR5 410 46646 D136 D A T I K V W D Y E T G D F E
Frog Xenopus laevis Q91854 518 59489 V235 R S E T S K G V Y C L Q Y D D
Zebra Danio Brachydanio rerio Q1LV15 415 45916 A141 R N V V Y A I A F N N P Y G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09990 665 75898 S259 Y S C S R I L S G H T G S V L
Sea Urchin Strong. purpuratus XP_784183 508 58645 L234 K I W D R Q S L Q C R T V L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39014 640 72817 K299 H C R I Q E F K G H M D G V L
Red Bread Mold Neurospora crassa Q01277 650 72171 K291 R Y K L S V L K G H E N G V T
Conservation
Percent
Protein Identity: 100 96 N.A. 96.2 N.A. 76.5 23.4 N.A. 83.3 22.1 79.1 21.7 N.A. N.A. N.A. 44.2 74.7
Protein Similarity: 100 96.2 N.A. 96.2 N.A. 84.3 41.7 N.A. 84.6 41.7 86.1 38.7 N.A. N.A. N.A. 56 84.3
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 6.6 N.A. 100 6.6 0 6.6 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 26.6 N.A. 100 20 6.6 26.6 N.A. N.A. N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 21.5
Protein Similarity: N.A. N.A. N.A. N.A. 41.8 41
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 16 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 8 8 0 0 39 0 0 0 16 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 8 0 0 0 8 8 8 24 % D
% Glu: 0 0 8 0 0 8 0 0 39 8 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 16 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 8 0 24 0 0 16 54 16 0 % G
% His: 8 0 0 0 8 0 0 0 0 24 0 0 0 0 0 % H
% Ile: 0 8 0 54 0 8 16 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 8 8 0 16 0 0 0 39 0 0 0 % K
% Leu: 39 0 0 8 0 0 16 8 0 0 8 0 0 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 16 0 0 0 0 0 0 0 47 16 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % P
% Gln: 0 39 0 0 39 8 0 0 8 0 0 8 0 0 0 % Q
% Arg: 31 0 47 0 16 0 39 0 0 0 8 0 0 0 0 % R
% Ser: 0 16 0 8 16 0 8 47 0 0 39 0 8 0 0 % S
% Thr: 0 0 8 8 0 0 0 0 0 8 16 8 0 0 8 % T
% Val: 0 0 16 16 0 16 0 8 0 0 0 0 8 62 0 % V
% Trp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 16 0 0 0 16 0 0 0 24 0 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _