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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXW11 All Species: 25.76
Human Site: S418 Identified Species: 47.22
UniProt: Q9UKB1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKB1 NP_036432.2 542 62091 S418 Y R D R L V V S G S S D N T I
Chimpanzee Pan troglodytes XP_518097 563 64534 S439 Y R D R L V V S G S S D N T I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852961 563 64548 S439 Y R D R L V V S G S S D N T I
Cat Felis silvestris
Mouse Mus musculus Q3ULA2 605 68904 S481 Y R D R L V V S G S S D N T I
Rat Rattus norvegicus Q5BK30 415 45841 K316 S C F D Y T G K L I A T A S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508141 638 72675 S514 Y R D R L V V S G S S D N T I
Chicken Gallus gallus Q9PTR5 410 46646 L311 S G K P G P F L L S G S R D K
Frog Xenopus laevis Q91854 518 59489 S410 Y R D R L V V S G S S D N T I
Zebra Danio Brachydanio rerio Q1LV15 415 45916 Q316 V C F N Y T G Q L I A T A S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09990 665 75898 S440 F D E K R I V S G A Y D G K I
Sea Urchin Strong. purpuratus XP_784183 508 58645 L409 V L E G H E E L V R C I R F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39014 640 72817 E478 P L T I K D V E N L A T D N T
Red Bread Mold Neurospora crassa Q01277 650 72171 P470 I L P P E Y E P D E E V L N G
Conservation
Percent
Protein Identity: 100 96 N.A. 96.2 N.A. 76.5 23.4 N.A. 83.3 22.1 79.1 21.7 N.A. N.A. N.A. 44.2 74.7
Protein Similarity: 100 96.2 N.A. 96.2 N.A. 84.3 41.7 N.A. 84.6 41.7 86.1 38.7 N.A. N.A. N.A. 56 84.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 100 6.6 100 0 N.A. N.A. N.A. 33.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 6.6 100 13.3 N.A. N.A. N.A. 66.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 21.5
Protein Similarity: N.A. N.A. N.A. N.A. 41.8 41
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 24 0 16 0 16 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 47 8 0 8 0 0 8 0 0 54 8 8 8 % D
% Glu: 0 0 16 0 8 8 16 8 0 8 8 0 0 0 0 % E
% Phe: 8 0 16 0 0 0 8 0 0 0 0 0 0 8 0 % F
% Gly: 0 8 0 8 8 0 16 0 54 0 8 0 8 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 8 0 8 0 0 0 16 0 8 0 0 54 % I
% Lys: 0 0 8 8 8 0 0 8 0 0 0 0 0 8 8 % K
% Leu: 0 24 0 0 47 0 0 16 24 8 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 0 47 16 0 % N
% Pro: 8 0 8 16 0 8 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 47 0 47 8 0 0 0 0 8 0 0 16 0 0 % R
% Ser: 16 0 0 0 0 0 0 54 0 54 47 8 0 16 0 % S
% Thr: 0 0 8 0 0 16 0 0 0 0 0 24 0 47 8 % T
% Val: 16 0 0 0 0 47 62 0 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 0 0 0 16 8 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _