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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW11
All Species:
21.82
Human Site:
Y248
Identified Species:
40
UniProt:
Q9UKB1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKB1
NP_036432.2
542
62091
Y248
K
G
V
Y
C
L
Q
Y
D
D
E
K
I
I
S
Chimpanzee
Pan troglodytes
XP_518097
563
64534
Y269
K
G
V
Y
C
L
Q
Y
D
D
E
K
I
I
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852961
563
64548
Y269
K
G
V
Y
C
L
Q
Y
D
D
E
K
I
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULA2
605
68904
Y311
K
G
V
Y
C
L
Q
Y
D
D
Q
K
I
V
S
Rat
Rattus norvegicus
Q5BK30
415
45841
T152
P
Y
G
D
K
I
A
T
G
S
F
D
K
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508141
638
72675
Y344
K
G
V
Y
C
L
Q
Y
D
D
E
K
I
I
S
Chicken
Gallus gallus
Q9PTR5
410
46646
K147
G
D
F
E
R
T
L
K
G
H
T
D
S
V
Q
Frog
Xenopus laevis
Q91854
518
59489
V246
Q
Y
D
D
Q
K
I
V
S
G
L
R
D
N
T
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
T152
P
Y
G
D
K
V
A
T
G
S
F
D
K
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09990
665
75898
Y270
G
S
V
L
C
L
Q
Y
D
N
R
V
I
I
S
Sea Urchin
Strong. purpuratus
XP_784183
508
58645
G245
T
V
L
M
G
H
T
G
S
V
L
C
L
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39014
640
72817
F310
D
G
V
L
T
L
Q
F
N
Y
R
L
L
F
T
Red Bread Mold
Neurospora crassa
Q01277
650
72171
L302
N
G
V
T
C
L
Q
L
D
D
N
I
L
A
T
Conservation
Percent
Protein Identity:
100
96
N.A.
96.2
N.A.
76.5
23.4
N.A.
83.3
22.1
79.1
21.7
N.A.
N.A.
N.A.
44.2
74.7
Protein Similarity:
100
96.2
N.A.
96.2
N.A.
84.3
41.7
N.A.
84.6
41.7
86.1
38.7
N.A.
N.A.
N.A.
56
84.3
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
0
N.A.
100
0
0
0
N.A.
N.A.
N.A.
60
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
6.6
20
6.6
N.A.
N.A.
N.A.
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
21.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
54
0
0
0
0
0
0
8
0
0
16
% C
% Asp:
8
8
8
24
0
0
0
0
54
47
0
24
8
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
31
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
16
0
0
8
0
% F
% Gly:
16
54
16
0
8
0
0
8
24
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
8
47
39
0
% I
% Lys:
39
0
0
0
16
8
0
8
0
0
0
39
16
0
0
% K
% Leu:
0
0
8
16
0
62
8
8
0
0
16
8
24
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
8
8
0
0
8
0
% N
% Pro:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
8
0
62
0
0
0
8
0
0
8
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
16
8
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
16
16
0
0
8
0
47
% S
% Thr:
8
0
0
8
8
8
8
16
0
0
8
0
0
16
24
% T
% Val:
0
8
62
0
0
8
0
8
0
8
0
8
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
39
0
0
0
47
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _