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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL2
All Species:
32.73
Human Site:
S130
Identified Species:
51.43
UniProt:
Q9UKC9
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKC9
NP_036289.2
423
47062
S130
Y
S
L
S
R
F
C
S
K
L
K
H
L
D
L
Chimpanzee
Pan troglodytes
XP_516355
501
55246
S208
Y
S
L
S
R
F
C
S
K
L
K
H
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001085981
393
43556
N132
C
P
L
L
E
Q
L
N
I
S
W
C
D
Q
V
Dog
Lupus familis
XP_542692
492
55087
S199
Y
S
L
S
R
F
C
S
K
L
K
H
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH16
423
46872
S130
Y
S
L
S
R
F
C
S
K
L
K
H
L
D
L
Rat
Rattus norvegicus
Q9QZH7
276
30442
D20
F
E
M
F
S
N
S
D
E
A
V
I
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521021
600
66255
S307
Y
S
L
S
K
F
C
S
K
L
K
H
L
D
L
Chicken
Gallus gallus
XP_418823
584
65781
S291
Y
S
L
S
R
F
C
S
K
L
K
H
L
D
L
Frog
Xenopus laevis
NP_001087065
436
48338
S143
T
S
L
S
K
F
C
S
K
L
R
Q
L
D
L
Zebra Danio
Brachydanio rerio
Q0P4D1
249
27093
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097271
651
69789
S358
Q
S
I
S
R
Y
C
S
K
L
T
A
I
N
L
Honey Bee
Apis mellifera
XP_393319
435
48744
P141
A
A
L
S
S
Y
C
P
K
L
Q
R
L
N
L
Nematode Worm
Caenorhab. elegans
P34284
466
52046
H175
E
N
L
G
R
Y
C
H
K
L
N
Y
L
N
L
Sea Urchin
Strong. purpuratus
XP_793918
431
47596
K138
Q
S
L
S
R
Y
S
K
K
L
S
Q
L
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
T294
A
A
V
G
E
L
C
T
S
L
E
R
L
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
70.6
85.1
N.A.
95.9
49.6
N.A.
63.3
65.4
75
21.5
N.A.
36.7
59.3
44.8
58.9
Protein Similarity:
100
84.4
81.3
85.5
N.A.
99.2
57.4
N.A.
68.5
69.6
86.4
35.4
N.A.
48.2
75.1
63.5
76.5
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
93.3
100
73.3
0
N.A.
53.3
46.6
46.6
46.6
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
100
100
86.6
0
N.A.
80
73.3
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
0
0
0
0
0
0
7
0
7
0
7
0
% A
% Cys:
7
0
0
0
0
0
74
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
7
47
0
% D
% Glu:
7
7
0
0
14
0
0
0
7
0
7
0
0
0
0
% E
% Phe:
7
0
0
7
0
47
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
40
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
7
0
0
7
7
0
0
% I
% Lys:
0
0
0
0
14
0
0
7
74
0
40
0
0
7
7
% K
% Leu:
0
0
74
7
0
7
7
0
0
80
0
0
74
0
74
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
7
0
7
0
0
7
0
7
27
0
% N
% Pro:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
7
0
0
0
0
7
14
0
7
0
% Q
% Arg:
0
0
0
0
54
0
0
0
0
0
7
14
0
0
0
% R
% Ser:
0
60
0
67
14
0
14
54
7
7
7
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
40
0
0
0
0
27
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _