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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL2
All Species:
23.64
Human Site:
S146
Identified Species:
37.14
UniProt:
Q9UKC9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKC9
NP_036289.2
423
47062
S146
S
C
V
S
I
T
N
S
S
L
K
G
I
S
E
Chimpanzee
Pan troglodytes
XP_516355
501
55246
S224
S
C
V
S
I
T
N
S
S
L
K
G
I
S
E
Rhesus Macaque
Macaca mulatta
XP_001085981
393
43556
V148
K
D
G
I
Q
A
L
V
R
G
C
G
G
L
K
Dog
Lupus familis
XP_542692
492
55087
S215
S
C
V
S
I
T
N
S
S
L
K
G
I
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH16
423
46872
S146
S
C
V
S
V
T
N
S
S
L
K
G
I
S
E
Rat
Rattus norvegicus
Q9QZH7
276
30442
I36
P
K
E
L
L
L
R
I
F
S
F
L
D
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521021
600
66255
S323
S
C
V
S
I
T
N
S
S
L
K
G
L
S
E
Chicken
Gallus gallus
XP_418823
584
65781
S307
S
C
V
A
I
T
N
S
S
L
K
G
L
S
E
Frog
Xenopus laevis
NP_001087065
436
48338
L159
S
C
T
S
I
T
N
L
S
L
K
A
I
S
E
Zebra Danio
Brachydanio rerio
Q0P4D1
249
27093
S9
A
T
I
D
S
L
M
S
L
C
A
F
S
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097271
651
69789
N374
S
C
S
N
I
T
D
N
S
L
K
Y
L
S
D
Honey Bee
Apis mellifera
XP_393319
435
48744
I157
S
C
P
E
I
S
D
I
S
M
K
N
L
S
K
Nematode Worm
Caenorhab. elegans
P34284
466
52046
R191
N
C
S
S
I
T
D
R
A
M
K
Y
I
G
D
Sea Urchin
Strong. purpuratus
XP_793918
431
47596
N154
S
C
T
A
I
T
D
N
A
L
K
S
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
K310
S
F
Q
H
F
T
D
K
G
M
R
A
I
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
70.6
85.1
N.A.
95.9
49.6
N.A.
63.3
65.4
75
21.5
N.A.
36.7
59.3
44.8
58.9
Protein Similarity:
100
84.4
81.3
85.5
N.A.
99.2
57.4
N.A.
68.5
69.6
86.4
35.4
N.A.
48.2
75.1
63.5
76.5
P-Site Identity:
100
100
6.6
100
N.A.
93.3
0
N.A.
93.3
86.6
80
6.6
N.A.
53.3
40
40
46.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
6.6
N.A.
100
100
80
20
N.A.
86.6
73.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
0
7
0
0
14
0
7
14
0
0
7
% A
% Cys:
0
74
0
0
0
0
0
0
0
7
7
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
34
0
0
0
0
0
7
0
20
% D
% Glu:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
47
% E
% Phe:
0
7
0
0
7
0
0
0
7
0
7
7
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
7
7
0
47
7
14
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
67
0
0
14
0
0
0
0
47
0
0
% I
% Lys:
7
7
0
0
0
0
0
7
0
0
74
0
0
0
20
% K
% Leu:
0
0
0
7
7
14
7
7
7
60
0
7
34
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
20
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
47
14
0
0
0
7
0
0
0
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
7
0
7
0
0
0
0
% R
% Ser:
74
0
14
47
7
7
0
47
60
7
0
7
7
67
0
% S
% Thr:
0
7
14
0
0
74
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
40
0
7
0
0
7
0
0
0
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _