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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL2
All Species:
42.73
Human Site:
T170
Identified Species:
67.14
UniProt:
Q9UKC9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKC9
NP_036289.2
423
47062
T170
L
S
W
C
D
Q
I
T
K
D
G
I
E
A
L
Chimpanzee
Pan troglodytes
XP_516355
501
55246
T248
L
S
W
C
D
Q
I
T
K
D
G
I
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001085981
393
43556
Y172
L
E
D
E
A
L
K
Y
I
G
A
H
C
P
E
Dog
Lupus familis
XP_542692
492
55087
T239
L
S
W
C
D
Q
I
T
K
D
G
I
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH16
423
46872
T170
L
S
W
C
D
Q
I
T
K
E
G
I
E
A
L
Rat
Rattus norvegicus
Q9QZH7
276
30442
L60
R
A
W
N
V
L
A
L
D
G
S
N
W
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521021
600
66255
T347
L
S
W
C
D
Q
V
T
K
E
G
I
E
A
L
Chicken
Gallus gallus
XP_418823
584
65781
T331
L
S
W
C
D
Q
I
T
K
D
G
I
E
A
L
Frog
Xenopus laevis
NP_001087065
436
48338
S183
I
S
W
C
D
Q
I
S
K
D
G
V
Q
A
L
Zebra Danio
Brachydanio rerio
Q0P4D1
249
27093
K33
R
M
L
P
A
S
V
K
D
R
L
L
R
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097271
651
69789
S398
V
S
W
C
H
L
I
S
E
N
G
V
E
A
L
Honey Bee
Apis mellifera
XP_393319
435
48744
T181
L
S
W
C
E
L
L
T
D
N
G
V
E
A
L
Nematode Worm
Caenorhab. elegans
P34284
466
52046
Q215
I
S
W
C
D
A
I
Q
D
R
G
V
Q
I
I
Sea Urchin
Strong. purpuratus
XP_793918
431
47596
S178
I
S
W
C
D
Q
I
S
D
N
G
I
E
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
S334
L
S
D
C
Y
F
V
S
C
K
G
L
E
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
70.6
85.1
N.A.
95.9
49.6
N.A.
63.3
65.4
75
21.5
N.A.
36.7
59.3
44.8
58.9
Protein Similarity:
100
84.4
81.3
85.5
N.A.
99.2
57.4
N.A.
68.5
69.6
86.4
35.4
N.A.
48.2
75.1
63.5
76.5
P-Site Identity:
100
100
6.6
100
N.A.
93.3
6.6
N.A.
86.6
100
73.3
0
N.A.
53.3
60
40
73.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
13.3
N.A.
100
100
100
20
N.A.
86.6
86.6
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
14
7
7
0
0
0
7
0
0
74
0
% A
% Cys:
0
0
0
80
0
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
0
0
14
0
60
0
0
0
34
34
0
0
0
0
0
% D
% Glu:
0
7
0
7
7
0
0
0
7
14
0
0
67
0
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
14
80
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
20
0
0
0
0
0
60
0
7
0
0
47
0
14
14
% I
% Lys:
0
0
0
0
0
0
7
7
47
7
0
0
0
0
0
% K
% Leu:
60
0
7
0
0
27
7
7
0
0
7
14
0
0
67
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
0
0
0
0
0
20
0
7
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
54
0
7
0
0
0
0
14
7
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
14
0
0
7
0
7
% R
% Ser:
0
80
0
0
0
7
0
27
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
7
0
20
0
0
0
0
27
0
0
0
% V
% Trp:
0
0
80
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _