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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL2
All Species:
49.39
Human Site:
Y399
Identified Species:
77.62
UniProt:
Q9UKC9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKC9
NP_036289.2
423
47062
Y399
P
H
V
K
V
H
A
Y
F
A
P
V
T
P
P
Chimpanzee
Pan troglodytes
XP_516355
501
55246
Y477
P
H
V
K
V
H
A
Y
F
A
P
V
T
P
P
Rhesus Macaque
Macaca mulatta
XP_001085981
393
43556
Y369
P
N
I
K
V
H
A
Y
F
A
P
V
T
P
P
Dog
Lupus familis
XP_542692
492
55087
Y468
P
H
V
K
V
H
A
Y
F
A
P
V
T
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH16
423
46872
Y399
P
H
V
K
V
H
A
Y
F
A
P
V
T
P
P
Rat
Rattus norvegicus
Q9QZH7
276
30442
G256
L
Q
S
L
C
A
S
G
C
S
N
I
T
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521021
600
66255
Y576
P
D
V
K
V
H
A
Y
F
A
P
V
T
P
P
Chicken
Gallus gallus
XP_418823
584
65781
Y560
P
H
V
K
V
H
A
Y
F
A
P
V
T
P
P
Frog
Xenopus laevis
NP_001087065
436
48338
Y412
P
N
I
K
V
H
A
Y
F
A
P
V
T
P
P
Zebra Danio
Brachydanio rerio
Q0P4D1
249
27093
R229
P
L
I
T
D
K
S
R
E
A
L
Q
N
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097271
651
69789
Y627
P
N
I
K
V
H
A
Y
F
A
P
G
T
P
P
Honey Bee
Apis mellifera
XP_393319
435
48744
Y411
P
N
I
K
V
H
A
Y
F
A
P
V
T
P
P
Nematode Worm
Caenorhab. elegans
P34284
466
52046
Y442
P
N
I
E
I
H
A
Y
F
A
P
V
T
P
P
Sea Urchin
Strong. purpuratus
XP_793918
431
47596
Y407
P
N
V
K
V
H
A
Y
F
A
P
V
T
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
I586
P
H
I
K
K
V
L
I
E
K
W
K
V
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
70.6
85.1
N.A.
95.9
49.6
N.A.
63.3
65.4
75
21.5
N.A.
36.7
59.3
44.8
58.9
Protein Similarity:
100
84.4
81.3
85.5
N.A.
99.2
57.4
N.A.
68.5
69.6
86.4
35.4
N.A.
48.2
75.1
63.5
76.5
P-Site Identity:
100
100
86.6
100
N.A.
100
6.6
N.A.
93.3
100
86.6
13.3
N.A.
80
86.6
73.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
93.3
100
100
26.6
N.A.
93.3
100
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
80
0
0
87
0
0
0
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
7
0
0
0
0
14
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% G
% His:
0
40
0
0
0
80
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
47
0
7
0
0
7
0
0
0
7
0
0
7
% I
% Lys:
0
0
0
80
7
7
0
0
0
7
0
7
0
0
0
% K
% Leu:
7
7
0
7
0
0
7
0
0
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
94
0
0
0
0
0
0
0
0
0
80
0
0
80
80
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
14
0
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
87
7
0
% T
% Val:
0
0
47
0
74
7
0
0
0
0
0
74
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _