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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRTO4 All Species: 15.15
Human Site: S225 Identified Species: 23.81
UniProt: Q9UKD2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKD2 NP_057267.2 239 27560 S225 M G D D L P E S A S E S T E E
Chimpanzee Pan troglodytes XP_001158792 192 22055 A179 G D D L P E S A S E S T E E S
Rhesus Macaque Macaca mulatta XP_001092057 239 27473 S225 M G D D L P E S A S E S A E E
Dog Lupus familis XP_544532 240 27523 S225 M G E D L P E S A S E S A E E
Cat Felis silvestris
Mouse Mus musculus Q9D0I8 239 27527 S225 M D D D L P E S A P E S E G E
Rat Rattus norvegicus NP_001100167 193 22144 P180 D D L P E S A P E S E G E S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515818 467 51925 V386 L G T E A E G V R W D L S S A
Chicken Gallus gallus XP_425751 242 28035 E225 L V G D E E D E E D E K E E E
Frog Xenopus laevis NP_001079849 240 27461 K225 L G G E T Q E K S E A E D M D
Zebra Danio Brachydanio rerio NP_001017657 242 27717 D225 L T D G D D D D E T K E A E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610554 256 29423 E226 V E D D V N D E E Q A D S A M
Honey Bee Apis mellifera XP_393683 245 28217 E225 I S Q D D T K E N L E E H E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784045 340 38813 S327 D D A P D S K S R S D G D D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33201 236 27039 N223 K V S A Y Y D N D S S T V E S
Red Bread Mold Neurospora crassa Q7S302 252 28311 Y225 F R V K L L A Y W S A A S G E
Conservation
Percent
Protein Identity: 100 80.3 98.3 93.7 N.A. 93.3 74.4 N.A. 41.3 77.6 73.7 70.2 N.A. 51.5 52.2 N.A. 43.5
Protein Similarity: 100 80.3 98.7 97.9 N.A. 96.2 77.4 N.A. 46.6 89.6 89.5 85.9 N.A. 69.1 71.8 N.A. 56.1
P-Site Identity: 100 13.3 93.3 86.6 N.A. 73.3 20 N.A. 6.6 26.6 13.3 13.3 N.A. 13.3 26.6 N.A. 13.3
P-Site Similarity: 100 33.3 93.3 93.3 N.A. 73.3 20 N.A. 33.3 40 40 46.6 N.A. 40 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 42.4
Protein Similarity: N.A. N.A. N.A. N.A. 52.3 60.7
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 0 14 7 27 0 20 7 20 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 27 40 47 20 7 27 7 7 7 14 7 14 7 20 % D
% Glu: 0 7 7 14 14 20 34 20 27 14 47 20 27 54 54 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 34 14 7 0 0 7 0 0 0 0 14 0 14 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 7 0 0 14 7 0 0 7 7 0 0 0 % K
% Leu: 27 0 7 7 34 7 0 0 0 7 0 7 0 0 0 % L
% Met: 27 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 7 0 7 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 14 7 27 0 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 14 0 0 0 0 0 0 % R
% Ser: 0 7 7 0 0 14 7 34 14 47 14 27 20 14 14 % S
% Thr: 0 7 7 0 7 7 0 0 0 7 0 14 7 0 0 % T
% Val: 7 14 7 0 7 0 0 7 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 7 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _