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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNIK
All Species:
20.61
Human Site:
S742
Identified Species:
64.76
UniProt:
Q9UKE5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKE5
NP_001155032.1
1360
154943
S742
T
P
S
S
Q
P
S
S
Q
G
G
S
Q
P
G
Chimpanzee
Pan troglodytes
XP_001164831
1360
154955
S742
T
P
S
S
Q
P
S
S
Q
G
G
S
Q
P
G
Rhesus Macaque
Macaca mulatta
XP_001088063
1359
154811
S742
T
P
S
S
Q
P
S
S
Q
G
G
S
Q
P
G
Dog
Lupus familis
XP_862336
1305
149038
S687
T
P
S
S
Q
P
S
S
Q
G
G
S
Q
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P83510
1323
150348
S705
S
G
S
S
S
S
S
S
T
P
S
S
Q
P
S
Rat
Rattus norvegicus
Q924I2
873
98660
V289
A
I
E
L
L
D
K
V
N
N
P
D
H
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422794
1360
155252
S742
T
P
S
S
Q
P
S
S
Q
G
G
S
Q
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23356
1096
122486
A512
P
E
D
L
D
V
L
A
S
E
L
S
K
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.8
95.2
N.A.
96
24.8
N.A.
N.A.
94.7
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
Protein Similarity:
100
99.9
99.9
95.7
N.A.
96.9
38.5
N.A.
N.A.
96.7
N.A.
N.A.
N.A.
N.A.
N.A.
59.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
46.6
0
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
53.3
0
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
13
0
0
0
0
0
13
0
0
0
% D
% Glu:
0
13
13
0
0
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
63
63
0
0
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
25
13
0
13
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% N
% Pro:
13
63
0
0
0
63
0
0
0
13
13
0
0
75
0
% P
% Gln:
0
0
0
0
63
0
0
0
63
0
0
0
75
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
75
75
13
13
75
75
13
0
13
88
0
13
13
% S
% Thr:
63
0
0
0
0
0
0
0
13
0
0
0
0
0
13
% T
% Val:
0
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _