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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNIK All Species: 18.18
Human Site: Y76 Identified Species: 57.14
UniProt: Q9UKE5 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKE5 NP_001155032.1 1360 154943 Y76 E I N M L K K Y S H H R N I A
Chimpanzee Pan troglodytes XP_001164831 1360 154955 Y76 E I N M L K K Y S H H R N I A
Rhesus Macaque Macaca mulatta XP_001088063 1359 154811 Y76 E I N M L K K Y S H H R N I A
Dog Lupus familis XP_862336 1305 149038 L70 K N T K G N T L K E E W I A Y
Cat Felis silvestris
Mouse Mus musculus P83510 1323 150348 Y76 E I N M L K K Y S H H R N I A
Rat Rattus norvegicus Q924I2 873 98660
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422794 1360 155252 Y72 E I N M L K K Y S H H R N I A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23356 1096 122486
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.8 95.2 N.A. 96 24.8 N.A. N.A. 94.7 N.A. N.A. N.A. N.A. N.A. 45.3 N.A.
Protein Similarity: 100 99.9 99.9 95.7 N.A. 96.9 38.5 N.A. N.A. 96.7 N.A. N.A. N.A. N.A. N.A. 59.1 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 0 N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 63 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 63 0 0 0 0 0 0 0 0 13 13 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 63 63 0 0 0 0 % H
% Ile: 0 63 0 0 0 0 0 0 0 0 0 0 13 63 0 % I
% Lys: 13 0 0 13 0 63 63 0 13 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 63 0 0 13 0 0 0 0 0 0 0 % L
% Met: 0 0 0 63 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 63 0 0 13 0 0 0 0 0 0 63 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 63 0 0 0 0 0 0 % S
% Thr: 0 0 13 0 0 0 13 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _