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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
34.85
Human Site:
S337
Identified Species:
54.76
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
S337
G
M
M
Q
S
G
L
S
R
E
L
F
E
S
W
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
S337
G
M
M
Q
S
G
L
S
R
E
L
F
E
S
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
S337
G
M
M
Q
S
G
L
S
R
E
L
F
E
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
S337
G
M
I
Q
N
G
L
S
R
E
L
F
E
S
W
Rat
Rattus norvegicus
Q3MHC2
600
67822
R291
T
W
T
N
Q
K
I
R
K
T
F
V
Q
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
K276
C
V
E
G
T
L
A
K
H
I
M
S
E
P
E
Chicken
Gallus gallus
Q5ZIH0
600
68170
R291
T
W
T
N
Q
K
I
R
K
T
F
V
Q
R
N
Frog
Xenopus laevis
Q9W799
783
88968
S338
P
D
L
E
C
G
F
S
R
E
L
F
I
Q
W
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
R291
T
W
T
N
Q
K
I
R
K
T
F
V
Q
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
T339
P
D
L
E
S
G
F
T
R
D
L
F
V
Q
W
Honey Bee
Apis mellifera
XP_395515
686
77564
S344
G
M
M
Q
S
G
L
S
R
E
L
F
E
S
W
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S338
Q
D
M
E
S
G
F
S
R
E
L
F
L
D
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
A336
A
S
L
E
A
G
F
A
R
E
I
F
V
E
W
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
S347
G
M
L
Q
S
G
L
S
R
D
L
L
E
R
W
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
S367
G
M
L
Q
N
G
V
S
R
E
L
L
E
R
W
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
0
N.A.
6.6
0
46.6
0
N.A.
40
100
60
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
26.6
20
60
20
N.A.
66.6
100
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
33.3
73.3
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
86.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
7
0
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
14
0
0
0
7
0
% D
% Glu:
0
0
7
27
0
0
0
0
0
60
0
0
54
7
7
% E
% Phe:
0
0
0
0
0
0
27
0
0
0
20
60
0
0
0
% F
% Gly:
47
0
0
7
0
74
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
20
0
0
7
7
0
7
0
0
% I
% Lys:
0
0
0
0
0
20
0
7
20
0
0
0
0
0
0
% K
% Leu:
0
0
34
0
0
7
40
0
0
0
67
14
7
0
0
% L
% Met:
0
47
34
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
20
14
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
14
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
47
20
0
0
0
0
0
0
0
20
14
0
% Q
% Arg:
0
0
0
0
0
0
0
20
74
0
0
0
0
34
0
% R
% Ser:
0
7
0
0
47
0
0
60
0
0
0
7
0
34
0
% S
% Thr:
20
0
20
0
7
0
0
7
0
20
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
7
0
0
0
0
20
14
0
0
% V
% Trp:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
74
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _