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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
18.18
Human Site:
S378
Identified Species:
28.57
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
S378
P
E
E
I
T
T
M
S
G
Q
K
L
P
L
K
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
S378
P
E
E
I
T
T
M
S
G
Q
K
L
P
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
S378
P
E
E
I
T
T
M
S
G
Q
K
L
P
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
S378
P
E
E
I
T
T
M
S
G
Q
K
L
P
L
K
Rat
Rattus norvegicus
Q3MHC2
600
67822
Q332
P
G
M
L
H
A
G
Q
S
L
Q
I
F
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
I317
Y
Q
Q
T
S
E
F
I
R
A
L
K
P
P
H
Chicken
Gallus gallus
Q5ZIH0
600
68170
Q332
P
G
M
L
H
A
G
Q
S
L
Q
I
F
R
K
Frog
Xenopus laevis
Q9W799
783
88968
I379
P
S
E
R
I
I
D
I
E
L
R
K
R
V
K
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
Q332
P
G
M
L
H
A
G
Q
S
L
Q
I
F
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
E380
C
A
P
G
K
Q
I
E
L
D
V
R
R
R
V
Honey Bee
Apis mellifera
XP_395515
686
77564
S385
P
E
E
I
T
T
M
S
G
Q
K
L
P
L
K
Nematode Worm
Caenorhab. elegans
O17403
843
95598
V379
A
E
R
A
N
D
G
V
L
K
H
E
D
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
V377
P
P
P
K
F
V
K
V
T
M
S
K
R
V
P
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
N388
P
D
T
I
P
S
I
N
N
P
E
I
T
I
P
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
M408
P
E
Q
I
Q
A
V
M
S
R
N
I
A
G
A
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
6.6
13.3
20
13.3
N.A.
0
100
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
26.6
33.3
33.3
33.3
N.A.
6.6
100
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
27
0
0
0
7
0
0
7
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
7
0
0
7
0
0
7
0
0
% D
% Glu:
0
47
40
0
0
7
0
7
7
0
7
7
0
0
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
20
0
0
% F
% Gly:
0
20
0
7
0
0
27
0
34
0
0
0
0
7
0
% G
% His:
0
0
0
0
20
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
0
0
47
7
7
14
14
0
0
0
34
0
7
0
% I
% Lys:
0
0
0
7
7
0
7
0
0
7
34
20
0
7
60
% K
% Leu:
0
0
0
20
0
0
0
0
14
27
7
34
0
34
7
% L
% Met:
0
0
20
0
0
0
34
7
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
7
7
0
7
0
0
0
0
% N
% Pro:
80
7
14
0
7
0
0
0
0
7
0
0
40
7
14
% P
% Gln:
0
7
14
0
7
7
0
20
0
34
20
0
0
0
0
% Q
% Arg:
0
0
7
7
0
0
0
0
7
7
7
7
20
27
0
% R
% Ser:
0
7
0
0
7
7
0
34
27
0
7
0
0
0
0
% S
% Thr:
0
0
7
7
34
34
0
0
7
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
7
7
14
0
0
7
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _