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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
19.39
Human Site:
S387
Identified Species:
30.48
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
S387
Q
K
L
P
L
K
M
S
V
D
Y
I
S
F
S
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
S387
Q
K
L
P
L
K
M
S
V
D
Y
I
S
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
S387
Q
K
L
P
L
K
M
S
V
D
Y
I
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
S387
Q
K
L
P
L
K
M
S
V
D
Y
I
S
F
S
Rat
Rattus norvegicus
Q3MHC2
600
67822
A341
L
Q
I
F
R
K
W
A
G
N
E
K
N
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
I326
A
L
K
P
P
H
V
I
L
V
H
G
E
Q
N
Chicken
Gallus gallus
Q5ZIH0
600
68170
A341
L
Q
I
F
R
K
W
A
G
N
E
K
N
M
V
Frog
Xenopus laevis
Q9W799
783
88968
E388
L
R
K
R
V
K
L
E
G
K
E
L
E
E
Y
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
A341
L
Q
I
F
K
K
W
A
G
N
E
K
N
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
L389
D
V
R
R
R
V
D
L
E
G
A
E
L
E
E
Honey Bee
Apis mellifera
XP_395515
686
77564
S394
Q
K
L
P
L
K
M
S
V
D
Y
I
S
F
S
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S388
K
H
E
D
R
L
I
S
L
V
V
K
K
R
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
A386
M
S
K
R
V
P
L
A
G
E
E
L
I
A
Y
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
R397
P
E
I
T
I
P
R
R
C
Q
V
E
E
I
S
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
R417
R
N
I
A
G
A
R
R
G
P
G
G
D
A
E
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
0
100
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
40
N.A.
33.3
40
33.3
40
N.A.
0
100
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
7
0
27
0
0
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
7
0
0
34
0
0
7
0
0
% D
% Glu:
0
7
7
0
0
0
0
7
7
7
34
14
20
14
14
% E
% Phe:
0
0
0
20
0
0
0
0
0
0
0
0
0
34
0
% F
% Gly:
0
0
0
0
7
0
0
0
40
7
7
14
0
0
0
% G
% His:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
34
0
7
0
7
7
0
0
0
34
7
7
0
% I
% Lys:
7
34
20
0
7
60
0
0
0
7
0
27
7
0
0
% K
% Leu:
27
7
34
0
34
7
14
7
14
0
0
14
7
0
0
% L
% Met:
7
0
0
0
0
0
34
0
0
0
0
0
0
20
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
20
0
0
20
0
7
% N
% Pro:
7
0
0
40
7
14
0
0
0
7
0
0
0
0
0
% P
% Gln:
34
20
0
0
0
0
0
0
0
7
0
0
0
7
0
% Q
% Arg:
7
7
7
20
27
0
14
14
0
0
0
0
0
7
0
% R
% Ser:
0
7
0
0
0
0
0
40
0
0
0
0
34
0
40
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
14
7
7
0
34
14
14
0
0
0
27
% V
% Trp:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _