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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF3 All Species: 25.15
Human Site: S482 Identified Species: 39.52
UniProt: Q9UKF6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKF6 NP_057291.1 684 77486 S482 P E Q G Q R V S G I L V K R N
Chimpanzee Pan troglodytes XP_001154609 684 77528 S482 P E Q G Q R V S G I L V K R N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540075 684 77455 S482 P E Q G Q R V S G I L V K R N
Cat Felis silvestris
Mouse Mus musculus Q9QXK7 684 77510 S482 P E Q G Q R V S G I L V K R N
Rat Rattus norvegicus Q3MHC2 600 67822 P407 Q L V G Q A E P E S V L L V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505542 595 67415 S393 P E Q G Q R V S G I L V K R N
Chicken Gallus gallus Q5ZIH0 600 68170 P407 Q L I R Q A E P R N V L L V H
Frog Xenopus laevis Q9W799 783 88968 E494 V P E L Q V T E D E K T K L E
Zebra Danio Brachydanio rerio Q503E1 598 67573 P407 Q L I R M A E P R N M L L V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3D6 756 85400 N498 F V P M E E Q N K E N V K K E
Honey Bee Apis mellifera XP_395515 686 77564 S489 P K P G Q T L S G V L V K R N
Nematode Worm Caenorhab. elegans O17403 843 95598 F492 T K K S F P M F P Y I E E K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKF9 739 82121 N502 M D R G A M H N G G D V D G R
Baker's Yeast Sacchar. cerevisiae Q06224 779 87655 L538 D I V V S G I L V S D D K N F
Red Bread Mold Neurospora crassa Q8WZS6 850 94060 T543 S T E P Q L I T G V L V Q N D
Conservation
Percent
Protein Identity: 100 99.8 N.A. 99.4 N.A. 97.8 33 N.A. 82.8 33.7 21.2 33 N.A. 20.3 71.2 20.8 N.A.
Protein Similarity: 100 99.8 N.A. 99.7 N.A. 99.1 50.5 N.A. 85.8 51.4 41.5 51.9 N.A. 42.4 81.9 39.9 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 6.6 13.3 0 N.A. 13.3 66.6 0 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 33.3 N.A. 100 26.6 20 20 N.A. 33.3 86.6 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.4 39.2 37.8
Protein Similarity: N.A. N.A. N.A. 42.7 59 55.7
P-Site Identity: N.A. N.A. N.A. 20 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. 40 13.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 20 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 0 0 0 0 7 0 14 7 7 0 7 % D
% Glu: 0 34 14 0 7 7 20 7 7 14 0 7 7 0 14 % E
% Phe: 7 0 0 0 7 0 0 7 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 54 0 7 0 0 54 7 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 20 % H
% Ile: 0 7 14 0 0 0 14 0 0 34 7 0 0 0 0 % I
% Lys: 0 14 7 0 0 0 0 0 7 0 7 0 60 14 0 % K
% Leu: 0 20 0 7 0 7 7 7 0 0 47 20 20 7 0 % L
% Met: 7 0 0 7 7 7 7 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 14 0 14 7 0 0 14 40 % N
% Pro: 40 7 14 7 0 7 0 20 7 0 0 0 0 0 0 % P
% Gln: 20 0 34 0 67 0 7 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 7 14 0 34 0 0 14 0 0 0 0 40 7 % R
% Ser: 7 0 0 7 7 0 0 40 0 14 0 0 0 0 0 % S
% Thr: 7 7 0 0 0 7 7 7 0 0 0 7 0 0 0 % T
% Val: 7 7 14 7 0 7 34 0 7 14 14 60 0 20 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _