KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
19.09
Human Site:
S611
Identified Species:
30
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
S611
K
L
E
M
H
V
Y
S
K
R
L
E
I
M
L
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
S611
K
L
E
M
H
V
Y
S
K
R
L
E
I
M
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
S611
K
L
E
M
H
V
Y
S
K
R
L
E
I
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
S611
K
L
E
M
H
V
Y
S
K
R
L
E
V
M
L
Rat
Rattus norvegicus
Q3MHC2
600
67822
R529
K
E
Q
E
T
A
L
R
V
Y
S
H
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
S522
K
I
D
M
D
I
Y
S
K
R
L
E
I
M
L
Chicken
Gallus gallus
Q5ZIH0
600
68170
L528
R
K
E
H
E
T
V
L
R
V
Y
N
H
L
K
Frog
Xenopus laevis
Q9W799
783
88968
G657
E
R
E
L
K
D
E
G
E
D
M
E
M
Q
V
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
L528
P
H
S
D
T
D
T
L
S
R
I
Y
T
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
V648
D
G
R
L
G
M
R
V
K
A
I
E
A
P
M
Honey Bee
Apis mellifera
XP_395515
686
77564
C615
D
R
M
H
F
K
E
C
L
I
E
M
L
Q
E
Nematode Worm
Caenorhab. elegans
O17403
843
95598
I652
S
D
A
L
L
A
D
I
Q
F
K
E
V
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
E641
D
S
E
V
G
K
T
E
R
D
M
R
S
L
L
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
S688
H
D
H
N
N
V
Q
S
N
A
Q
G
K
I
D
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
D702
T
H
S
P
L
P
A
D
K
N
P
H
S
H
L
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
73.3
6.6
13.3
13.3
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
93.3
26.6
53.3
20
N.A.
40
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
14
7
0
0
14
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
20
14
7
7
7
14
7
7
0
14
0
0
0
0
7
% D
% Glu:
7
7
47
7
7
0
14
7
7
0
7
54
0
0
14
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
14
0
0
7
0
0
0
7
0
0
0
% G
% His:
7
14
7
14
27
0
0
0
0
0
0
14
7
14
0
% H
% Ile:
0
7
0
0
0
7
0
7
0
7
14
0
27
7
0
% I
% Lys:
40
7
0
0
7
14
0
0
47
0
7
0
7
7
7
% K
% Leu:
0
27
0
20
14
0
7
14
7
0
34
0
14
14
54
% L
% Met:
0
0
7
34
0
7
0
0
0
0
14
7
7
34
7
% M
% Asn:
0
0
0
7
7
0
0
0
7
7
0
7
0
0
0
% N
% Pro:
7
0
0
7
0
7
0
0
0
0
7
0
0
7
0
% P
% Gln:
0
0
7
0
0
0
7
0
7
0
7
0
0
14
0
% Q
% Arg:
7
14
7
0
0
0
7
7
14
40
0
7
0
0
0
% R
% Ser:
7
7
14
0
0
0
0
40
7
0
7
0
14
7
7
% S
% Thr:
7
0
0
0
14
7
14
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
7
0
34
7
7
7
7
0
0
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
7
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _