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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
25.45
Human Site:
T451
Identified Species:
40
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
T451
E
V
H
N
P
R
N
T
E
A
V
T
L
N
F
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
T451
E
V
H
N
P
R
N
T
E
A
V
T
L
N
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
T451
E
V
H
N
P
R
N
T
E
A
V
T
L
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
T451
E
V
H
N
P
R
N
T
E
A
V
T
L
N
F
Rat
Rattus norvegicus
Q3MHC2
600
67822
S388
K
M
Q
V
E
Y
M
S
F
S
A
H
A
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
K373
T
L
N
F
R
G
E
K
L
A
K
V
M
G
F
Chicken
Gallus gallus
Q5ZIH0
600
68170
S388
K
M
Q
V
E
Y
M
S
F
S
A
H
A
D
A
Frog
Xenopus laevis
Q9W799
783
88968
K438
Q
I
T
S
H
K
A
K
H
D
L
M
M
K
N
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
S388
K
L
Q
V
E
Y
M
S
F
S
A
H
A
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
E464
H
V
M
F
P
Y
H
E
E
K
V
K
C
D
E
Honey Bee
Apis mellifera
XP_395515
686
77564
T458
E
I
H
N
P
R
N
T
V
A
V
E
L
Y
F
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S450
A
P
I
V
P
R
H
S
E
K
D
F
R
S
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
S461
D
G
F
V
P
P
S
S
S
V
A
P
M
F
P
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
C465
H
V
F
N
P
R
N
C
V
E
V
D
L
E
F
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
C496
K
V
F
S
P
R
N
C
E
E
L
R
I
P
F
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
13.3
0
0
0
N.A.
26.6
73.3
26.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
33.3
33.3
40
33.3
N.A.
40
80
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
0
0
40
27
0
20
0
20
% A
% Cys:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
7
7
0
27
0
% D
% Glu:
34
0
0
0
20
0
7
7
47
14
0
7
0
7
7
% E
% Phe:
0
0
20
14
0
0
0
0
20
0
0
7
0
7
60
% F
% Gly:
0
7
0
0
0
7
0
0
0
0
0
0
0
7
0
% G
% His:
14
0
34
0
7
0
14
0
7
0
0
20
0
0
0
% H
% Ile:
0
14
7
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
27
0
0
0
0
7
0
14
0
14
7
7
0
7
0
% K
% Leu:
0
14
0
0
0
0
0
0
7
0
14
0
40
0
0
% L
% Met:
0
14
7
0
0
0
20
0
0
0
0
7
20
0
0
% M
% Asn:
0
0
7
40
0
0
47
0
0
0
0
0
0
27
7
% N
% Pro:
0
7
0
0
67
7
0
0
0
0
0
7
0
7
7
% P
% Gln:
7
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
54
0
0
0
0
0
7
7
0
0
% R
% Ser:
0
0
0
14
0
0
7
34
7
20
0
0
0
7
0
% S
% Thr:
7
0
7
0
0
0
0
34
0
0
0
27
0
0
0
% T
% Val:
0
47
0
34
0
0
0
0
14
7
47
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
27
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _