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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
26.67
Human Site:
T638
Identified Species:
41.9
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
T638
D
D
S
I
L
S
V
T
V
D
G
K
T
A
N
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
T638
D
D
S
I
L
S
V
T
V
D
G
K
T
A
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
T638
D
G
S
V
L
S
V
T
V
D
G
K
T
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
T638
D
D
S
V
L
S
V
T
V
D
G
K
T
A
N
Rat
Rattus norvegicus
Q3MHC2
600
67822
S555
D
G
S
V
T
V
E
S
I
L
I
Q
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
T549
D
G
S
I
L
S
I
T
V
D
G
K
T
A
N
Chicken
Gallus gallus
Q5ZIH0
600
68170
E554
P
D
G
S
I
T
V
E
S
I
L
I
Q
A
T
Frog
Xenopus laevis
Q9W799
783
88968
T700
E
E
S
E
I
I
P
T
L
E
P
L
P
S
N
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
I553
H
V
P
D
G
T
V
I
V
E
S
I
V
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
A677
T
L
T
L
E
T
L
A
D
D
E
I
P
I
H
Honey Bee
Apis mellifera
XP_395515
686
77564
T641
K
G
E
K
L
Y
V
T
V
D
G
K
K
A
H
Nematode Worm
Caenorhab. elegans
O17403
843
95598
D691
T
S
N
L
M
I
D
D
K
N
R
E
E
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
G678
K
Q
F
L
S
S
K
G
V
Q
V
E
F
A
G
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
D722
F
T
L
F
L
N
K
D
E
Y
A
S
N
K
E
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
T750
S
P
T
T
K
A
I
T
S
P
S
E
E
T
A
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
20
N.A.
86.6
20
20
13.3
N.A.
6.6
53.3
0
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
46.6
N.A.
93.3
33.3
60
26.6
N.A.
40
60
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
0
0
7
0
7
60
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
27
0
7
0
0
7
14
7
47
0
0
0
7
0
% D
% Glu:
7
7
7
7
7
0
7
7
7
14
7
20
14
0
7
% E
% Phe:
7
0
7
7
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
27
7
0
7
0
0
7
0
0
40
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% H
% Ile:
0
0
0
20
14
14
14
7
7
7
7
20
0
14
0
% I
% Lys:
14
0
0
7
7
0
14
0
7
0
0
40
7
7
7
% K
% Leu:
0
7
7
20
47
0
7
0
7
7
7
7
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
7
0
0
7
0
40
% N
% Pro:
7
7
7
0
0
0
7
0
0
7
7
0
14
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
7
0
7
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
7
47
7
7
40
0
7
14
0
14
7
0
7
0
% S
% Thr:
14
7
14
7
7
20
0
54
0
0
0
0
34
7
7
% T
% Val:
0
7
0
20
0
7
47
0
54
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _