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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
25.76
Human Site:
Y110
Identified Species:
40.48
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y110
Y
R
W
L
L
S
D
Y
V
K
V
S
N
I
S
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y110
Y
R
W
L
L
S
D
Y
V
K
V
S
N
I
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y110
Y
R
W
L
L
S
D
Y
V
K
V
S
N
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y110
Y
R
W
L
L
S
D
Y
V
K
V
S
N
I
S
Rat
Rattus norvegicus
Q3MHC2
600
67822
Y107
C
P
I
L
L
E
D
Y
R
K
I
A
V
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
R93
L
Y
T
G
D
F
S
R
Q
E
D
R
H
L
M
Chicken
Gallus gallus
Q5ZIH0
600
68170
Y107
C
P
I
L
L
E
D
Y
R
K
I
T
V
D
K
Frog
Xenopus laevis
Q9W799
783
88968
L101
G
Q
M
F
M
Y
D
L
Y
Q
S
R
H
N
T
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
F107
C
P
I
L
L
E
D
F
R
K
I
T
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
L101
G
Q
M
F
M
Y
D
L
Y
M
S
H
F
N
M
Honey Bee
Apis mellifera
XP_395515
686
77564
Y117
Y
R
W
L
L
S
D
Y
I
K
V
S
N
I
A
Nematode Worm
Caenorhab. elegans
O17403
843
95598
M101
G
Q
M
F
I
Y
D
M
V
Y
S
H
L
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
Q101
G
L
L
T
M
Y
D
Q
F
L
S
R
K
Q
V
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
F107
Y
R
W
L
L
R
D
F
V
R
V
T
S
I
G
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
S122
Y
K
W
L
I
Q
D
S
V
R
V
G
N
T
S
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
0
33.3
6.6
26.6
N.A.
6.6
86.6
13.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
46.6
N.A.
20
46.6
40
46.6
N.A.
20
100
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
60
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
86.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
94
0
0
0
7
0
0
27
0
% D
% Glu:
0
0
0
0
0
20
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
7
0
14
7
0
0
0
7
0
0
% F
% Gly:
27
0
0
7
0
0
0
0
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
14
14
0
0
% H
% Ile:
0
0
20
0
14
0
0
0
7
0
20
0
0
40
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
54
0
0
7
0
20
% K
% Leu:
7
7
7
67
60
0
0
14
0
7
0
0
7
7
0
% L
% Met:
0
0
20
0
20
0
0
7
0
7
0
0
0
0
14
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
40
14
0
% N
% Pro:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
0
0
0
7
0
7
7
7
0
0
0
7
0
% Q
% Arg:
0
40
0
0
0
7
0
7
20
14
0
20
0
0
0
% R
% Ser:
0
0
0
0
0
34
7
7
0
0
27
34
7
0
34
% S
% Thr:
0
0
7
7
0
0
0
0
0
0
0
20
0
7
7
% T
% Val:
0
0
0
0
0
0
0
0
47
0
47
0
20
0
14
% V
% Trp:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
7
0
0
0
27
0
47
14
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _