KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
23.64
Human Site:
Y269
Identified Species:
37.14
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y269
E
L
H
D
I
P
I
Y
Y
A
S
S
L
A
K
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y269
E
L
H
D
I
P
I
Y
Y
A
S
S
L
A
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y269
E
L
H
D
I
P
I
Y
Y
A
S
S
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y269
E
L
H
D
I
P
I
Y
Y
A
S
S
L
A
K
Rat
Rattus norvegicus
Q3MHC2
600
67822
R231
K
V
H
E
T
V
E
R
G
G
K
V
L
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
K217
I
N
N
P
F
V
F
K
H
I
S
N
L
K
S
Chicken
Gallus gallus
Q5ZIH0
600
68170
G232
V
H
E
T
V
E
R
G
G
K
V
L
I
P
V
Frog
Xenopus laevis
Q9W799
783
88968
A267
G
L
G
V
Y
S
L
A
L
L
N
N
V
S
Y
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
G232
V
H
E
T
V
E
R
G
G
K
V
L
I
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
A267
G
L
M
A
Y
S
L
A
L
L
N
N
V
S
Y
Honey Bee
Apis mellifera
XP_395515
686
77564
Y276
E
L
H
E
I
P
I
Y
Y
A
S
S
L
A
K
Nematode Worm
Caenorhab. elegans
O17403
843
95598
V266
G
L
S
T
Y
N
L
V
M
M
S
H
V
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
Y264
R
G
F
S
F
P
I
Y
F
L
T
Y
V
S
S
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
F277
G
G
G
Q
V
P
I
F
Y
A
S
N
L
A
K
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
Y285
E
Y
Q
K
Y
P
I
Y
Y
A
S
N
L
A
R
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
13.3
0
6.6
0
N.A.
6.6
93.3
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
33.3
13.3
40
13.3
N.A.
40
100
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
20
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
14
0
47
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
27
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
40
0
14
14
0
14
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
14
0
7
7
7
0
0
0
0
0
0
% F
% Gly:
27
14
14
0
0
0
0
14
20
7
0
0
0
0
0
% G
% His:
0
14
40
0
0
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
34
0
54
0
0
7
0
0
14
7
0
% I
% Lys:
7
0
0
7
0
0
0
7
0
14
7
0
0
7
40
% K
% Leu:
0
54
0
0
0
0
20
0
14
20
0
14
60
0
0
% L
% Met:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
7
0
0
0
0
14
34
0
0
0
% N
% Pro:
0
0
0
7
0
54
0
0
0
0
0
0
0
14
7
% P
% Gln:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
14
7
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
7
0
14
0
0
0
0
60
34
0
20
20
% S
% Thr:
0
0
0
20
7
0
0
0
0
0
7
0
0
0
0
% T
% Val:
14
7
0
7
20
14
0
7
0
0
14
7
27
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
27
0
0
47
47
0
0
7
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _