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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
25.76
Human Site:
Y285
Identified Species:
40.48
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y285
C
M
A
V
Y
Q
T
Y
V
N
A
M
N
D
K
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y285
C
M
A
V
Y
Q
T
Y
V
N
A
M
N
D
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y285
C
M
A
V
Y
Q
T
Y
V
N
A
M
N
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y285
C
M
A
V
Y
Q
T
Y
V
N
A
M
N
D
K
Rat
Rattus norvegicus
Q3MHC2
600
67822
E247
F
A
L
G
R
A
Q
E
L
C
I
L
L
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
P233
D
H
F
D
D
I
G
P
S
V
V
M
A
S
P
Chicken
Gallus gallus
Q5ZIH0
600
68170
L248
A
L
G
R
A
Q
E
L
C
I
L
L
E
T
F
Frog
Xenopus laevis
Q9W799
783
88968
Q283
V
V
E
F
S
K
S
Q
V
E
W
M
S
D
K
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
L248
A
L
G
R
A
Q
E
L
C
I
L
L
E
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
Q283
V
I
E
F
A
K
S
Q
I
E
W
M
S
D
K
Honey Bee
Apis mellifera
XP_395515
686
77564
Y292
C
M
A
V
Y
Q
T
Y
V
N
A
M
N
D
K
Nematode Worm
Caenorhab. elegans
O17403
843
95598
Q282
V
V
Q
F
A
K
S
Q
L
E
W
M
N
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
F280
T
I
D
Y
V
K
S
F
L
E
W
M
S
D
S
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
Y293
C
M
S
V
F
Q
T
Y
V
N
M
M
N
D
D
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
Y301
C
M
L
V
Y
Q
T
Y
V
G
S
M
N
D
N
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
6.6
6.6
26.6
6.6
N.A.
20
100
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
6.6
20
53.3
20
N.A.
53.3
100
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
73.3
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
34
0
27
7
0
0
0
0
34
0
7
0
0
% A
% Cys:
47
0
0
0
0
0
0
0
14
7
0
0
0
0
0
% C
% Asp:
7
0
7
7
7
0
0
0
0
0
0
0
0
67
7
% D
% Glu:
0
0
14
0
0
0
14
7
0
27
0
0
14
14
0
% E
% Phe:
7
0
7
20
7
0
0
7
0
0
0
0
0
0
14
% F
% Gly:
0
0
14
7
0
0
7
0
0
7
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
7
0
0
7
14
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
54
% K
% Leu:
0
14
14
0
0
0
0
14
20
0
14
20
7
0
0
% L
% Met:
0
47
0
0
0
0
0
0
0
0
7
80
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
40
0
0
54
0
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
0
0
7
0
0
60
7
20
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
14
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
7
0
27
0
7
0
7
0
20
7
7
% S
% Thr:
7
0
0
0
0
0
47
0
0
0
0
0
0
14
7
% T
% Val:
20
14
0
47
7
0
0
0
54
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
27
0
0
0
0
% W
% Tyr:
0
0
0
7
40
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _