KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
23.33
Human Site:
Y435
Identified Species:
36.67
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y435
K
A
A
L
I
R
E
Y
E
D
N
D
E
V
H
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y435
K
A
A
L
I
R
E
Y
E
D
N
D
E
V
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y435
K
A
A
L
I
R
E
Y
E
D
N
D
E
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y435
K
A
A
L
I
R
E
Y
E
D
N
D
E
V
H
Rat
Rattus norvegicus
Q3MHC2
600
67822
M372
S
G
Q
R
K
L
E
M
E
G
R
Q
M
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
N358
D
V
H
I
E
V
H
N
P
R
N
T
E
A
V
Chicken
Gallus gallus
Q5ZIH0
600
68170
M372
S
G
Q
R
K
L
E
M
E
G
R
Q
I
L
E
Frog
Xenopus laevis
Q9W799
783
88968
S420
K
E
A
D
L
D
S
S
D
D
S
D
V
E
E
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
M372
N
G
Q
K
K
L
E
M
E
G
R
A
T
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
S422
E
E
E
S
S
S
E
S
E
D
D
I
E
M
S
Honey Bee
Apis mellifera
XP_395515
686
77564
Y442
K
A
A
L
Q
R
E
Y
E
D
D
P
N
T
T
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S433
R
Q
A
Q
A
N
E
S
D
D
S
D
D
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
D424
K
A
S
H
G
S
D
D
N
S
S
E
P
M
I
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
F447
K
S
A
L
L
S
N
F
A
S
L
K
G
T
D
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
G465
P
V
V
I
L
V
H
G
E
V
H
N
M
M
R
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
13.3
13.3
26.6
13.3
N.A.
26.6
60
26.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
20
20
46.6
20
N.A.
46.6
66.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
54
0
7
0
0
0
7
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
7
7
7
14
54
14
40
7
7
20
% D
% Glu:
7
14
7
0
7
0
67
0
67
0
0
7
40
7
20
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
7
0
0
7
0
20
0
0
7
0
0
% G
% His:
0
0
7
7
0
0
14
0
0
0
7
0
0
0
27
% H
% Ile:
0
0
0
14
27
0
0
0
0
0
0
7
7
0
7
% I
% Lys:
54
0
0
7
20
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
40
20
20
0
0
0
0
7
0
0
20
0
% L
% Met:
0
0
0
0
0
0
0
20
0
0
0
0
14
20
0
% M
% Asn:
7
0
0
0
0
7
7
7
7
0
34
7
7
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% P
% Gln:
0
7
20
7
7
0
0
0
0
0
0
14
0
0
0
% Q
% Arg:
7
0
0
14
0
34
0
0
0
7
20
0
0
0
7
% R
% Ser:
14
7
7
7
7
20
7
20
0
14
20
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
7
7
14
7
% T
% Val:
0
14
7
0
0
14
0
0
0
7
0
0
7
27
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _