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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
20.3
Human Site:
Y519
Identified Species:
31.9
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y519
K
Q
T
Q
A
I
P
Y
T
G
P
F
N
L
L
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y519
K
Q
T
Q
A
I
P
Y
T
G
P
F
N
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y519
K
Q
T
Q
A
I
P
Y
T
G
P
F
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y519
K
Q
T
Q
A
I
P
Y
T
G
P
F
Y
L
L
Rat
Rattus norvegicus
Q3MHC2
600
67822
V444
M
P
A
N
G
E
T
V
T
L
P
T
S
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
Y430
K
Q
T
Q
A
I
P
Y
T
G
P
F
N
L
L
Chicken
Gallus gallus
Q5ZIH0
600
68170
T444
M
P
A
N
G
E
T
T
T
I
F
T
N
P
S
Frog
Xenopus laevis
Q9W799
783
88968
I531
S
T
T
E
S
M
E
I
K
A
R
V
T
Y
I
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
T444
M
P
A
N
G
E
T
T
T
I
V
T
N
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
S535
E
K
P
T
K
L
I
S
Q
R
K
T
I
E
V
Honey Bee
Apis mellifera
XP_395515
686
77564
F526
I
Q
R
Q
S
V
Y
F
S
A
S
L
L
V
L
Nematode Worm
Caenorhab. elegans
O17403
843
95598
E529
R
K
G
Q
N
K
D
E
P
V
V
V
K
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
L539
I
V
T
V
S
C
S
L
V
K
M
D
Y
E
G
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
V575
R
E
R
Q
S
V
R
V
N
C
K
K
E
L
I
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
L580
A
C
K
Q
R
L
K
L
S
A
A
G
I
D
L
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
13.3
N.A.
100
13.3
6.6
13.3
N.A.
0
20
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
20
N.A.
100
13.3
33.3
13.3
N.A.
26.6
53.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
20
0
34
0
0
0
0
20
7
0
0
0
0
% A
% Cys:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% D
% Glu:
7
7
0
7
0
20
7
7
0
0
0
0
7
14
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
34
0
0
0
% F
% Gly:
0
0
7
0
20
0
0
0
0
34
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
34
7
7
0
14
0
0
14
0
14
% I
% Lys:
34
14
7
0
7
7
7
0
7
7
14
7
7
7
0
% K
% Leu:
0
0
0
0
0
14
0
14
0
7
0
7
7
40
47
% L
% Met:
20
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
20
7
0
0
0
7
0
0
0
40
0
0
% N
% Pro:
0
20
7
0
0
0
34
0
7
0
40
0
0
20
0
% P
% Gln:
0
40
0
60
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
14
0
14
0
7
0
7
0
0
7
7
0
0
0
7
% R
% Ser:
7
0
0
0
27
0
7
7
14
0
7
0
7
0
20
% S
% Thr:
0
7
47
7
0
0
20
14
54
0
0
27
7
0
0
% T
% Val:
0
7
0
7
0
14
0
14
7
7
14
14
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
34
0
0
0
0
14
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _