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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3
All Species:
19.7
Human Site:
Y677
Identified Species:
30.95
UniProt:
Q9UKF6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKF6
NP_057291.1
684
77486
Y677
E
L
A
A
Q
R
L
Y
E
A
L
T
P
V
H
Chimpanzee
Pan troglodytes
XP_001154609
684
77528
Y677
E
L
A
A
Q
R
L
Y
E
A
L
T
P
V
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540075
684
77455
Y677
E
L
A
A
Q
R
L
Y
E
A
L
T
P
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK7
684
77510
Y677
E
L
A
A
Q
R
L
Y
E
A
L
T
P
V
H
Rat
Rattus norvegicus
Q3MHC2
600
67822
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505542
595
67415
Y588
E
L
A
A
Q
R
L
Y
D
A
L
T
P
V
H
Chicken
Gallus gallus
Q5ZIH0
600
68170
K593
Y
L
T
S
L
L
K
K
G
L
P
Q
S
T
S
Frog
Xenopus laevis
Q9W799
783
88968
V739
E
G
I
H
A
E
F
V
G
G
V
L
V
C
N
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
W716
E
F
S
G
G
V
L
W
C
S
N
G
T
L
A
Honey Bee
Apis mellifera
XP_395515
686
77564
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S730
S
Q
E
S
L
A
I
S
E
S
G
K
E
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
I717
S
G
P
Q
Q
I
L
I
E
G
P
L
C
E
D
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
K761
E
C
N
S
N
P
L
K
G
R
V
E
S
L
L
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
R789
Q
Q
L
K
A
R
E
R
A
E
V
E
R
L
E
Conservation
Percent
Protein Identity:
100
99.8
N.A.
99.4
N.A.
97.8
33
N.A.
82.8
33.7
21.2
33
N.A.
20.3
71.2
20.8
N.A.
Protein Similarity:
100
99.8
N.A.
99.7
N.A.
99.1
50.5
N.A.
85.8
51.4
41.5
51.9
N.A.
42.4
81.9
39.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
93.3
6.6
6.6
0
N.A.
13.3
0
13.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
13.3
20
0
N.A.
40
0
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
39.2
37.8
Protein Similarity:
N.A.
N.A.
N.A.
42.7
59
55.7
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
34
14
7
0
0
7
34
0
0
0
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
7
0
0
0
7
7
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% D
% Glu:
54
0
7
0
0
7
7
0
40
7
0
14
7
7
14
% E
% Phe:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
0
7
7
0
0
0
20
14
7
7
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
34
% H
% Ile:
0
0
7
0
0
7
7
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
7
14
0
0
0
7
0
0
0
% K
% Leu:
0
40
7
0
14
7
54
0
0
7
34
14
0
20
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
14
0
34
0
0
% P
% Gln:
7
14
0
7
40
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
40
0
7
0
7
0
0
7
0
0
% R
% Ser:
14
0
7
20
0
0
0
7
0
14
0
0
14
0
7
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
34
7
7
0
% T
% Val:
0
0
0
0
0
7
0
7
0
0
20
0
7
40
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _