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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CROT
All Species:
27.27
Human Site:
T182
Identified Species:
46.15
UniProt:
Q9UKG9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKG9
NP_066974.2
612
70178
T182
S
I
M
N
Y
F
R
T
E
S
E
G
R
S
P
Chimpanzee
Pan troglodytes
XP_519181
612
70113
T182
S
I
M
N
Y
F
R
T
E
S
E
G
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001106063
612
70108
T182
S
I
M
N
Y
F
R
T
E
S
E
G
R
S
P
Dog
Lupus familis
XP_539402
612
70074
T182
S
I
K
S
Y
F
K
T
E
S
E
G
H
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC50
612
70246
T182
S
I
M
N
Y
F
K
T
E
S
E
G
H
C
P
Rat
Rattus norvegicus
P11466
612
70284
T182
S
I
M
N
Y
F
K
T
E
S
E
G
H
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508909
667
75073
T182
S
V
V
N
Y
F
R
T
G
K
E
A
P
S
P
Chicken
Gallus gallus
Q90YJ9
640
72605
C188
T
L
V
A
Q
K
S
C
V
M
P
E
P
E
H
Frog
Xenopus laevis
Q7ZXE1
659
74538
G242
E
L
L
T
D
E
K
G
R
H
L
L
V
L
R
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
T183
T
L
V
A
Q
K
S
T
V
M
P
E
P
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
E253
S
Q
F
L
P
S
R
E
R
L
N
D
E
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
T183
T
Q
I
R
K
Q
K
T
N
D
G
N
E
H
V
Sea Urchin
Strong. purpuratus
XP_790326
610
68809
P183
P
L
Y
R
Y
F
K
P
E
R
E
G
P
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
Y237
N
Q
D
T
N
I
F
Y
S
V
Y
E
N
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
84.6
N.A.
85.6
84.8
N.A.
68.8
29.2
27.7
28.5
N.A.
25.9
N.A.
27.7
45.1
Protein Similarity:
100
99.8
99
91.1
N.A.
93.1
92.4
N.A.
79.1
49.5
46.2
49.9
N.A.
45.6
N.A.
46.8
63.5
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
60
0
0
6.6
N.A.
13.3
N.A.
6.6
40
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
73.3
20
20
26.6
N.A.
13.3
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
22
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
8
0
8
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
8
50
0
58
22
15
15
0
% E
% Phe:
0
0
8
0
0
58
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
8
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
22
8
15
% H
% Ile:
0
43
8
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
15
43
0
0
8
0
0
0
0
0
% K
% Leu:
0
29
8
8
0
0
0
0
0
8
8
8
0
8
0
% L
% Met:
0
0
36
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
8
0
0
43
8
0
0
0
8
0
8
8
8
8
0
% N
% Pro:
8
0
0
0
8
0
0
8
0
0
15
0
29
0
58
% P
% Gln:
0
22
0
0
15
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
0
0
36
0
15
8
0
0
22
0
15
% R
% Ser:
58
0
0
8
0
8
15
0
8
43
0
0
0
36
0
% S
% Thr:
22
0
0
15
0
0
0
65
0
0
0
0
0
0
0
% T
% Val:
0
8
22
0
0
0
0
0
15
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
58
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _