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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CROT All Species: 43.64
Human Site: Y35 Identified Species: 73.85
UniProt: Q9UKG9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKG9 NP_066974.2 612 70178 Y35 L E E S L K K Y L E S V K P F
Chimpanzee Pan troglodytes XP_519181 612 70113 Y35 L E E S L K K Y L E S V K P F
Rhesus Macaque Macaca mulatta XP_001106063 612 70108 Y35 L K E S L K K Y L E S V K P F
Dog Lupus familis XP_539402 612 70074 Y35 L E E S L K K Y L E S V K P F
Cat Felis silvestris
Mouse Mus musculus Q9DC50 612 70246 Y35 L E E S L K K Y L E S V K P F
Rat Rattus norvegicus P11466 612 70284 Y35 L E E S L K K Y L E S V K P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508909 667 75073 Y35 L E E S L K K Y L D S V K P F
Chicken Gallus gallus Q90YJ9 640 72605 Y38 L Q Q T L Q M Y L Q C M K H L
Frog Xenopus laevis Q7ZXE1 659 74538 Y66 F E D T I K R Y L N A Q R P L
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 E43 C M G H L V P E D Q F R K T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 Y103 L D E T M A D Y I R A L E P I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 Y35 L E A T L D R Y L E Y A A V V
Sea Urchin Strong. purpuratus XP_790326 610 68809 K39 H K Y L Q S V K P F L S E E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 Y89 L K S T L D K Y L Q T I R P F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 84.6 N.A. 85.6 84.8 N.A. 68.8 29.2 27.7 28.5 N.A. 25.9 N.A. 27.7 45.1
Protein Similarity: 100 99.8 99 91.1 N.A. 93.1 92.4 N.A. 79.1 49.5 46.2 49.9 N.A. 45.6 N.A. 46.8 63.5
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 33.3 33.3 13.3 N.A. 26.6 N.A. 40 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 73.3 73.3 20 N.A. 73.3 N.A. 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 0 0 15 8 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 8 0 0 15 8 0 8 8 0 0 0 0 0 % D
% Glu: 0 58 58 0 0 0 0 8 0 50 0 0 15 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 58 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 8 % I
% Lys: 0 22 0 0 0 58 58 8 0 0 0 0 65 0 8 % K
% Leu: 79 0 0 8 79 0 0 0 79 0 8 8 0 0 15 % L
% Met: 0 8 0 0 8 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 8 0 0 0 0 72 0 % P
% Gln: 0 8 8 0 8 8 0 0 0 22 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 15 0 0 8 0 8 15 0 0 % R
% Ser: 0 0 8 50 0 8 0 0 0 0 50 8 0 0 0 % S
% Thr: 0 0 0 36 0 0 0 0 0 0 8 0 0 8 0 % T
% Val: 0 0 0 0 0 8 8 0 0 0 0 50 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 86 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _