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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CROT All Species: 41.52
Human Site: Y429 Identified Species: 70.26
UniProt: Q9UKG9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKG9 NP_066974.2 612 70178 Y429 L A L Q L A Y Y R L H G H P G
Chimpanzee Pan troglodytes XP_519181 612 70113 Y429 L A L Q L A Y Y R L H G H P G
Rhesus Macaque Macaca mulatta XP_001106063 612 70108 Y429 L A L Q L A Y Y R L H G C P G
Dog Lupus familis XP_539402 612 70074 Y429 L A L Q L A Y Y R L T G C P G
Cat Felis silvestris
Mouse Mus musculus Q9DC50 612 70246 Y429 L A L Q L A Y Y R L H G R P G
Rat Rattus norvegicus P11466 612 70284 Y429 L A L Q L A Y Y R L H G R P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508909 667 75073 Y429 L A L Q L S Y Y R L Y G R P G
Chicken Gallus gallus Q90YJ9 640 72605 Y436 V A L Q L A F Y R C H R R L V
Frog Xenopus laevis Q7ZXE1 659 74538 L478 L S F Q M A F L R Q Y G K T T
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 Y431 V A L Q F T F Y R C H G R L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 Y520 L A L Q L A H Y K L Y G R L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 Y442 L I M Q L A H Y K T H G H L V
Sea Urchin Strong. purpuratus XP_790326 610 68809 Y427 L A L Q L A Y Y T A T G K P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 F484 Q V I Q L A V F K Y L K R Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 84.6 N.A. 85.6 84.8 N.A. 68.8 29.2 27.7 28.5 N.A. 25.9 N.A. 27.7 45.1
Protein Similarity: 100 99.8 99 91.1 N.A. 93.1 92.4 N.A. 79.1 49.5 46.2 49.9 N.A. 45.6 N.A. 46.8 63.5
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 80 53.3 33.3 46.6 N.A. 60 N.A. 53.3 73.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 93.3 66.6 60 60 N.A. 80 N.A. 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 79 0 0 0 86 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 15 0 0 15 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 8 0 22 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 86 0 0 58 % G
% His: 0 0 0 0 0 0 15 0 0 0 58 0 22 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 22 0 0 8 15 0 0 % K
% Leu: 79 0 79 0 86 0 0 8 0 58 8 0 0 29 8 % L
% Met: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 % P
% Gln: 8 0 0 100 0 0 0 0 0 8 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 72 0 0 8 50 0 0 % R
% Ser: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 8 8 15 0 0 8 8 % T
% Val: 15 8 0 0 0 0 8 0 0 0 0 0 0 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 58 86 0 8 22 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _