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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM21
All Species:
11.52
Human Site:
S193
Identified Species:
50.67
UniProt:
Q9UKJ8
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKJ8
NP_003804.1
722
80834
S193
E
F
E
E
A
E
N
S
A
L
E
P
K
S
A
Chimpanzee
Pan troglodytes
XP_001145699
722
80833
S193
E
F
E
E
A
E
N
S
A
L
E
P
K
S
A
Rhesus Macaque
Macaca mulatta
XP_001105948
722
80721
S193
G
F
E
E
A
E
N
S
A
L
E
P
K
S
A
Dog
Lupus familis
XP_537500
1476
165197
S949
K
F
E
E
V
K
K
S
T
L
K
Q
N
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI76
729
80831
K197
F
G
V
E
E
A
K
K
S
A
M
K
Q
N
Y
Rat
Rattus norvegicus
P70505
789
86122
E226
Q
G
S
S
K
T
D
E
L
L
A
L
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.1
38.6
N.A.
67.9
33
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.2
42.8
N.A.
79.6
50.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
40
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
60
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
17
0
0
50
17
17
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
0
0
0
0
17
0
% D
% Glu:
34
0
67
84
17
50
0
17
0
0
50
0
0
0
0
% E
% Phe:
17
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
17
17
34
17
0
0
17
17
50
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
17
84
0
17
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
50
0
0
0
0
0
17
17
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
17
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
17
17
0
0
0
67
17
0
0
0
17
67
0
% S
% Thr:
0
0
0
0
0
17
0
0
17
0
0
0
0
0
0
% T
% Val:
0
0
17
0
17
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _