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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJD2 All Species: 15.15
Human Site: T248 Identified Species: 37.04
UniProt: Q9UKL4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKL4 NP_065711.1 321 36093 T248 E C Y V S R P T E K T V F L V
Chimpanzee Pan troglodytes XP_524857 433 48312 G327 L P S Y A Q V G A Q E V E G E
Rhesus Macaque Macaca mulatta XP_001095298 435 48589 G329 L P S Y A Q V G A Q E V E G E
Dog Lupus familis XP_544602 321 36207 T248 E C Y V S R P T E K T V F L V
Cat Felis silvestris
Mouse Mus musculus O54851 321 36067 T248 E C Y V S R P T E K T V F L V
Rat Rattus norvegicus O70610 321 36033 T248 E C Y V S R P T E K T V F L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521627 199 22386 V143 F A V S G V C V L L N L A E L
Chicken Gallus gallus P36381 400 45598 A242 R R A L R R P A E E Q M G E V
Frog Xenopus laevis Q7ZXS7 377 43145 S277 E S R K K K P S A P P N Y H S
Zebra Danio Brachydanio rerio Q92052 380 43560 I274 V Q R P R A P I C R Q V P T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.8 28.5 96.5 N.A. 97.5 97.8 N.A. 42.3 26.7 24.1 24.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.4 40.2 98.4 N.A. 99 98.7 N.A. 51 42 43.2 43.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 100 100 N.A. 0 26.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 100 N.A. 100 100 N.A. 13.3 46.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 20 10 0 10 30 0 0 0 10 0 10 % A
% Cys: 0 40 0 0 0 0 10 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 50 0 0 0 0 0 0 0 50 10 20 0 20 20 20 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % F
% Gly: 0 0 0 0 10 0 0 20 0 0 0 0 10 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 10 10 0 0 0 40 0 0 0 0 0 % K
% Leu: 20 0 0 10 0 0 0 0 10 10 0 10 0 40 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 20 0 10 0 0 70 0 0 10 10 0 10 0 0 % P
% Gln: 0 10 0 0 0 20 0 0 0 20 20 0 0 0 0 % Q
% Arg: 10 10 20 0 20 50 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 10 20 10 40 0 0 10 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 40 0 0 40 0 0 10 0 % T
% Val: 10 0 10 40 0 10 20 10 0 0 0 70 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 40 20 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _