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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJD2
All Species:
16.67
Human Site:
Y243
Identified Species:
40.74
UniProt:
Q9UKL4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKL4
NP_065711.1
321
36093
Y243
C
I
K
E
V
E
C
Y
V
S
R
P
T
E
K
Chimpanzee
Pan troglodytes
XP_524857
433
48312
S322
G
Y
Q
E
T
L
P
S
Y
A
Q
V
G
A
Q
Rhesus Macaque
Macaca mulatta
XP_001095298
435
48589
S324
G
Y
Q
E
T
L
P
S
Y
A
Q
V
G
A
Q
Dog
Lupus familis
XP_544602
321
36207
Y243
C
I
K
E
V
E
C
Y
V
S
R
P
T
E
K
Cat
Felis silvestris
Mouse
Mus musculus
O54851
321
36067
Y243
C
I
K
E
V
E
C
Y
V
S
R
P
T
E
K
Rat
Rattus norvegicus
O70610
321
36033
Y243
C
I
K
E
V
E
C
Y
V
S
R
P
T
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521627
199
22386
V138
F
L
V
F
M
F
A
V
S
G
V
C
V
L
L
Chicken
Gallus gallus
P36381
400
45598
A237
I
L
K
R
I
R
R
A
L
R
R
P
A
E
E
Frog
Xenopus laevis
Q7ZXS7
377
43145
R272
R
K
E
I
Q
E
S
R
K
K
K
P
S
A
P
Zebra Danio
Brachydanio rerio
Q92052
380
43560
R269
A
R
H
Q
S
V
Q
R
P
R
A
P
I
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
28.5
96.5
N.A.
97.5
97.8
N.A.
42.3
26.7
24.1
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.4
40.2
98.4
N.A.
99
98.7
N.A.
51
42
43.2
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
13.3
53.3
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
10
0
20
10
0
10
30
0
% A
% Cys:
40
0
0
0
0
0
40
0
0
0
0
10
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
60
0
50
0
0
0
0
0
0
0
50
10
% E
% Phe:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
0
0
0
0
0
0
10
0
0
20
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
40
0
10
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
50
0
0
0
0
0
10
10
10
0
0
0
40
% K
% Leu:
0
20
0
0
0
20
0
0
10
0
0
0
0
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
20
0
10
0
0
70
0
0
10
% P
% Gln:
0
0
20
10
10
0
10
0
0
0
20
0
0
0
20
% Q
% Arg:
10
10
0
10
0
10
10
20
0
20
50
0
0
0
10
% R
% Ser:
0
0
0
0
10
0
10
20
10
40
0
0
10
0
0
% S
% Thr:
0
0
0
0
20
0
0
0
0
0
0
0
40
0
0
% T
% Val:
0
0
10
0
40
10
0
10
40
0
10
20
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
40
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _