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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM28
All Species:
16.67
Human Site:
S690
Identified Species:
40.74
UniProt:
Q9UKQ2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKQ2
NP_055080.2
775
87181
S690
A
M
V
I
R
H
Q
S
S
R
E
K
Q
K
K
Chimpanzee
Pan troglodytes
XP_519663
776
87192
S691
A
I
V
I
R
H
Q
S
S
R
E
K
Q
K
K
Rhesus Macaque
Macaca mulatta
XP_001106707
776
87167
S691
A
V
V
I
R
Q
Q
S
S
R
E
K
Q
K
K
Dog
Lupus familis
XP_850956
1004
113439
S916
A
V
V
I
W
H
Q
S
T
R
G
K
Q
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN6
793
88652
S693
A
I
V
I
Q
R
Q
S
A
R
R
K
Q
R
R
Rat
Rattus norvegicus
Q63180
789
89344
R690
G
L
V
I
L
L
I
R
Y
Q
K
C
I
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507646
518
58508
V440
T
K
C
G
D
G
K
V
C
S
N
G
E
C
V
Chicken
Gallus gallus
XP_001233496
804
88725
V688
V
L
L
F
R
F
R
V
F
K
K
S
S
H
T
Frog
Xenopus laevis
NP_001121218
534
58638
R456
K
K
P
G
D
V
C
R
A
A
K
D
D
C
D
Zebra Danio
Brachydanio rerio
NP_956931
843
93452
I681
L
V
Y
N
R
N
K
I
T
E
F
R
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
91.1
61.7
N.A.
68.9
37.9
N.A.
33.6
45.6
31.3
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
94.1
68.7
N.A.
80.7
57.5
N.A.
45.4
62.5
44.2
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
66.6
N.A.
53.3
20
N.A.
0
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
40
N.A.
13.3
40
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
10
0
10
0
0
10
0
20
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
0
0
10
10
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
30
0
10
0
10
% E
% Phe:
0
0
0
10
0
10
0
0
10
0
10
0
0
0
0
% F
% Gly:
10
0
0
20
0
10
0
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
30
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
20
0
60
0
0
10
10
0
0
0
0
10
0
0
% I
% Lys:
10
20
0
0
0
0
20
0
0
10
30
50
10
60
30
% K
% Leu:
10
20
10
0
10
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
50
0
0
10
0
0
50
0
0
% Q
% Arg:
0
0
0
0
50
10
10
20
0
50
10
10
0
10
20
% R
% Ser:
0
0
0
0
0
0
0
50
30
10
0
10
10
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
20
0
0
0
0
0
10
% T
% Val:
10
30
60
0
0
10
0
20
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _