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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAM28 All Species: 27.27
Human Site: Y59 Identified Species: 66.67
UniProt: Q9UKQ2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKQ2 NP_055080.2 775 87181 Y59 Q F E T E L K Y K M T I N G K
Chimpanzee Pan troglodytes XP_519663 776 87192 Y59 Q F E T E L K Y K M T V N G K
Rhesus Macaque Macaca mulatta XP_001106707 776 87167 Y60 Q F E T E L K Y K M T V N G K
Dog Lupus familis XP_850956 1004 113439 Y287 K F E T E L K Y K M T V N G K
Cat Felis silvestris
Mouse Mus musculus Q9JLN6 793 88652 Y61 T F E T E L R Y K M T V N G K
Rat Rattus norvegicus Q63180 789 89344 Y61 E Y E E E L L Y E I K L G R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507646 518 58508
Chicken Gallus gallus XP_001233496 804 88725 Y61 K Y D D T L E Y G I K A N G E
Frog Xenopus laevis NP_001121218 534 58638
Zebra Danio Brachydanio rerio NP_956931 843 93452 Y57 K Y P E Q L E Y D V A I D G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 91.1 61.7 N.A. 68.9 37.9 N.A. 33.6 45.6 31.3 35.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 94.1 68.7 N.A. 80.7 57.5 N.A. 45.4 62.5 44.2 52.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 86.6 N.A. 80 33.3 N.A. 0 26.6 0 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 66.6 N.A. 0 66.6 0 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 10 0 0 0 10 0 0 % D
% Glu: 10 0 60 20 60 0 20 0 10 0 0 0 0 0 10 % E
% Phe: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 10 70 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 20 0 20 0 0 0 % I
% Lys: 30 0 0 0 0 0 40 0 50 0 20 0 0 0 60 % K
% Leu: 0 0 0 0 0 80 10 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 30 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 10 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 50 10 0 0 0 0 0 50 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 40 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 30 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _