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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLK12 All Species: 15.15
Human Site: T83 Identified Species: 47.62
UniProt: Q9UKR0 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKR0 NP_062544.1 248 26734 T83 S L S Q L D W T E Q I R H S G
Chimpanzee Pan troglodytes XP_001174143 248 26822 T83 S L S Q L D W T E Q I R R S G
Rhesus Macaque Macaca mulatta XP_001116273 248 26784 T83 S L S H L D W T E Q I R H S G
Dog Lupus familis XP_854572 264 28831 T99 S L S R L D W T E K I R R S G
Cat Felis silvestris
Mouse Mus musculus Q61955 260 28505 P94 S L Q S R D Q P E Q E I Q V A
Rat Rattus norvegicus O88780 260 28491 P94 S L Q K R D E P E Q E I Q V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90629 248 26604 S86 N I D V Q E D S E V V R S S S
Frog Xenopus laevis P70059 244 26061 E83 I A L N E G T E Q F I D S Q K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 73.1 N.A. 47.3 46.5 N.A. N.A. 46.7 45.1 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 97.5 79.1 N.A. 58 59.6 N.A. N.A. 63.3 63.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 80 N.A. 33.3 33.3 N.A. N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 33.3 40 N.A. N.A. 53.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 75 13 0 0 0 0 13 0 0 0 % D
% Glu: 0 0 0 0 13 13 13 13 88 0 25 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 50 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 0 25 0 0 % H
% Ile: 13 13 0 0 0 0 0 0 0 0 63 25 0 0 0 % I
% Lys: 0 0 0 13 0 0 0 0 0 13 0 0 0 0 13 % K
% Leu: 0 75 13 0 50 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % P
% Gln: 0 0 25 25 13 0 13 0 13 63 0 0 25 13 0 % Q
% Arg: 0 0 0 13 25 0 0 0 0 0 0 63 25 0 0 % R
% Ser: 75 0 50 13 0 0 0 13 0 0 0 0 25 63 13 % S
% Thr: 0 0 0 0 0 0 13 50 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 0 0 0 13 13 0 0 25 0 % V
% Trp: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _