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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKZF2 All Species: 13.64
Human Site: S66 Identified Species: 33.33
UniProt: Q9UKS7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKS7 NP_001072994.1 526 59574 S66 E C D R K P L S R E D E I R G
Chimpanzee Pan troglodytes XP_001169617 544 59653 P74 E S S R L L G P D E R L L E K
Rhesus Macaque Macaca mulatta XP_001083355 526 59532 S66 E C D R K P L S R E D E I R G
Dog Lupus familis XP_850763 526 59494 S66 E C D R K P L S R E D E I R G
Cat Felis silvestris
Mouse Mus musculus P81183 526 59370 S66 E C D R Q P L S R E D E I R G
Rat Rattus norvegicus NP_001100386 313 35100
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510954 343 38834
Chicken Gallus gallus O42410 518 57568 M73 E N G R A C E M N G E E C A E
Frog Xenopus laevis Q6NRM0 453 49949 Q43 D K E A E T L Q G G T Q N H D
Zebra Danio Brachydanio rerio Q6DBW0 419 46136 L9 G E E K P E P L D F V K D F Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.7 99.8 99 N.A. 97.7 54.1 N.A. 61.4 52.8 20.7 23.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 68.3 100 99.6 N.A. 98.8 55.1 N.A. 63.6 68 34.9 40.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 100 N.A. 93.3 0 N.A. 0 20 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 0 N.A. 0 26.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 40 0 0 0 10 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 40 0 0 0 0 0 20 0 40 0 10 0 10 % D
% Glu: 60 10 20 0 10 10 10 0 0 50 10 50 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 10 0 10 0 0 0 10 0 10 20 0 0 0 0 40 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % I
% Lys: 0 10 0 10 30 0 0 0 0 0 0 10 0 0 10 % K
% Leu: 0 0 0 0 10 10 50 10 0 0 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 40 10 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 10 0 0 0 10 0 0 10 % Q
% Arg: 0 0 0 60 0 0 0 0 40 0 10 0 0 40 0 % R
% Ser: 0 10 10 0 0 0 0 40 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _