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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKZF2
All Species:
23.03
Human Site:
Y175
Identified Species:
56.3
UniProt:
Q9UKS7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKS7
NP_001072994.1
526
59574
Y175
F
K
C
P
F
C
S
Y
A
C
R
R
R
D
A
Chimpanzee
Pan troglodytes
XP_001169617
544
59653
Y181
F
K
C
P
F
C
N
Y
A
C
R
R
R
D
A
Rhesus Macaque
Macaca mulatta
XP_001083355
526
59532
Y175
F
K
C
P
F
C
S
Y
A
C
R
R
R
D
A
Dog
Lupus familis
XP_850763
526
59494
Y175
F
K
C
P
F
C
S
Y
A
C
R
R
R
D
A
Cat
Felis silvestris
Mouse
Mus musculus
P81183
526
59370
Y175
F
K
C
P
F
C
S
Y
A
C
R
R
R
D
A
Rat
Rattus norvegicus
NP_001100386
313
35100
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510954
343
38834
K11
S
V
L
S
P
V
G
K
P
H
K
C
N
Y
C
Chicken
Gallus gallus
O42410
518
57568
Y180
F
K
C
H
L
C
N
Y
A
C
R
R
R
D
A
Frog
Xenopus laevis
Q6NRM0
453
49949
I122
R
L
I
E
H
I
R
I
H
T
G
E
K
P
H
Zebra Danio
Brachydanio rerio
Q6DBW0
419
46136
T88
C
R
Y
C
N
Y
A
T
R
G
T
A
R
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
99.8
99
N.A.
97.7
54.1
N.A.
61.4
52.8
20.7
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.3
100
99.6
N.A.
98.8
55.1
N.A.
63.6
68
34.9
40.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
0
N.A.
0
80
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
6.6
86.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
60
0
0
10
0
0
60
% A
% Cys:
10
0
60
10
0
60
0
0
0
60
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
60
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% G
% His:
0
0
0
10
10
0
0
0
10
10
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
60
0
0
0
0
0
10
0
0
10
0
10
0
0
% K
% Leu:
0
10
10
0
10
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
20
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
50
10
0
0
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
10
0
10
0
60
60
70
0
0
% R
% Ser:
10
0
0
10
0
0
40
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% T
% Val:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _