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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO5
All Species:
8.48
Human Site:
S145
Identified Species:
20.74
UniProt:
Q9UKT4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT4
NP_001135994.1
447
50146
S145
T
S
R
L
Y
E
D
S
G
Y
S
S
F
S
L
Chimpanzee
Pan troglodytes
XP_518817
447
50085
S145
T
S
R
L
Y
E
D
S
G
Y
S
S
F
S
Q
Rhesus Macaque
Macaca mulatta
XP_001096104
448
50240
S146
T
S
R
L
Y
E
D
S
G
Y
S
S
F
S
Q
Dog
Lupus familis
XP_854840
639
71505
E337
L
E
T
S
G
P
Y
E
D
S
G
Y
S
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSG3
421
47490
N146
L
I
L
E
N
F
R
N
S
P
Q
A
R
L
L
Rat
Rattus norvegicus
Q66H04
664
73210
E204
D
C
G
L
F
E
V
E
C
L
S
P
I
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516380
351
39897
F81
Q
R
L
S
Y
R
G
F
Q
N
A
N
P
R
I
Chicken
Gallus gallus
XP_419681
397
44677
C127
L
P
L
A
G
N
L
C
S
T
P
E
H
C
L
Frog
Xenopus laevis
Q4V7W2
384
43153
R114
N
V
S
D
I
Q
V
R
D
T
P
K
N
L
M
Zebra Danio
Brachydanio rerio
Q0V967
384
43025
E114
L
D
S
L
E
R
S
E
E
N
C
V
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
57.9
N.A.
64.4
25.6
N.A.
43.1
44.2
38
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.4
62.1
N.A.
74.7
38.5
N.A.
57.4
60.6
52.3
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
6.6
20
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
6.6
N.A.
20
26.6
N.A.
26.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
10
10
0
10
0
0
10
0
% C
% Asp:
10
10
0
10
0
0
30
0
20
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
10
40
0
30
10
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
10
10
0
10
0
0
0
0
30
0
10
% F
% Gly:
0
0
10
0
20
0
10
0
30
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
40
0
30
50
0
0
10
0
0
10
0
0
0
20
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
10
10
0
10
0
20
0
10
10
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
0
10
20
10
10
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
10
0
10
0
0
0
30
% Q
% Arg:
0
10
30
0
0
20
10
10
0
0
0
0
10
10
0
% R
% Ser:
0
30
20
20
0
0
10
30
20
10
40
30
20
50
0
% S
% Thr:
30
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
20
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
40
0
10
0
0
30
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _