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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO4
All Species:
9.09
Human Site:
T58
Identified Species:
25
UniProt:
Q9UKT5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKT5
NP_036308.1
387
44136
T58
E
V
D
E
A
A
S
T
L
T
R
L
P
I
D
Chimpanzee
Pan troglodytes
XP_001137206
388
44407
T58
E
V
D
E
A
A
S
T
L
T
R
L
P
I
D
Rhesus Macaque
Macaca mulatta
XP_001088308
387
44051
T58
E
V
D
E
A
A
S
T
L
T
R
L
P
I
D
Dog
Lupus familis
XP_546338
387
44107
A58
E
A
G
E
E
A
S
A
L
T
R
L
P
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHQ0
385
43763
R59
E
E
T
S
A
L
T
R
L
P
V
D
V
Q
L
Rat
Rattus norvegicus
NP_001101142
431
48554
A102
E
E
A
E
E
T
S
A
L
T
R
L
P
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507650
303
34340
Chicken
Gallus gallus
XP_429141
386
43015
L60
E
V
S
A
L
Q
A
L
P
I
D
V
Q
L
Y
Frog
Xenopus laevis
NP_001121213
384
43489
P62
D
S
L
L
C
D
L
P
V
D
M
Q
L
Y
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
98.4
89.9
N.A.
88.1
79.5
N.A.
52.9
57.3
54.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95
99.4
93.2
N.A.
92.2
83.5
N.A.
63.3
70
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
20
66.6
N.A.
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
26.6
66.6
N.A.
0
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
45
45
12
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
34
0
0
12
0
0
0
12
12
12
0
0
56
% D
% Glu:
78
23
0
56
23
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
56
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
12
12
12
12
12
67
0
0
56
12
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
12
12
0
0
56
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
12
12
12
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
56
0
0
0
0
% R
% Ser:
0
12
12
12
0
0
56
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
12
12
34
0
56
0
0
0
0
0
% T
% Val:
0
45
0
0
0
0
0
0
12
0
12
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _